Vancouver, British Columbia--(Newsfile Corp. - June 22, 2021) - Defence Therapeutics Inc. (CSE: DTC) ("Defence" or the "Company"), is pleased to announce major breakthrough advances in its pre-clinical research program on its AccuTOX (free AccumTM or AccumTM variants) molecules as potent anti-cancer agents.
The AccumTM technology platform is very efficient at enhancing intracellular delivery of proteins of pharmacological interests such as ADCs or vaccine antigens. Defence's scientific team recently identified a novel function for the use of "free" AccumTM and its recently developed variants as anti-cancer molecules.
"The AccumTM technology platform is displaying multiple targets in its versatility. You can use it with ADCs or any other protein of interest such as vaccine antigens to enhance their intracellular delivery to target cells. We additionally discovered that when delivered without direct linking onto protein, the AccumTM moiety behaves as a toxic "bullet" to cancer cells. Such discovery re-enforces the idea that AccumTM can be exploited for various applications without the need to develop other unrelated molecules," said Sebastien Plouffe, CEO of Defence Therapeutics.
The Defence team engineered a large library of AccumTM variants (over 50 so far). They are currently being testing for their therapeutic efficacy against breast, colon, melanoma and lymphoma cancers. In addition, a new strategy is currently being developed to engineer an "intelligent" Poly-AccuTOX molecule (a chain of various AccuTOX molecules) capable of selectively killing a wide range of cancer cells without collateral side effects.
Global Immunotherapy Market size to reach USD 117 billion by 2026 according to Market Study Report LLC.
Defence Therapeutics is a publicly-traded biotechnology company working on engineering the next generation vaccines and ADC products using its proprietary platform. The core of Defence Therapeutics platform is the ACCUMTM technology, which enables precision delivery of vaccine antigens or ADCs in their intact form to target cells by inducing their entrapment escape. As a result, increased efficacy and potency can be reached against catastrophic illness such as cancer and infectious diseases.
For further information:
Sebastien Plouffe, President, CEO and Director
P: (514) 947-2272
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