Techvest 7th Annual Healthcare Conference takes place 07
- 09 Nov. at the New York Palace Hotel in New York City. For in-depth
information about the event visit
http://www.rodmanandrenshaw.com/index.htm.
Below are profiles from Techvest 7th Annual Healthcare Conference presenters. News releases, web cast advisories, and photos are available at http://home.businesswire.com/portal/site/bwges-techvest-health-05/.
Business Wire is the official news wire service for the Techvest 7th Annual Healthcare Conference. -0- Company: Active Biotech AB Ticker Symbol & Exchange: ACTI.SE SEK Investor Relations Contact: Cecilia Hofvander Investor Relations Contact Phone: +46 46 19 11 22 or +46 701 89 11 22 Web: www.activebiotech.com Date of Presentation: Nov 8
Active Biotech AB is a biotechnology company focusing on research and development of pharmaceuticals. Active Biotech has a strong R&D portfolio with pipeline products focused on autoimmune/inflammatory diseases and cancer. Most advanced projects are laquinimod, an orally administered small molecule with unique immunomodulatory properties for the treatment of multiple sclerosis, as well as ANYARA for use in cancer immunotherapy with the primary indication non-small cell lung cancer. Further key projects in clinical development comprise the three orally administered compounds TASQ for prostate cancer 57-57 for SLE and RhuDex(R) for RA. -0- Company: Adeza Biomedical Ticker Symbol & Exchange: Nasdaq: ADZA Investor Relations Contact: Brandi Floberg Investor Relations Contact Phone: 310-691-7100 Web: www.adeza.com Date of Presentation: November 9, 2005 at 11:15 a.m. ET
Adeza designs, manufactures and markets innovative products for women's health. Adeza's initial focus is on reproductive healthcare, using its proprietary technologies to predict preterm birth and assess infertility. Adeza's principal product is a patented diagnostic test, FullTerm(TM) The Fetal Fibronectin Test, which utilizes a single-use, disposable cassette and is analyzed on Adeza's patented TLiIQ(R) System. This product is approved by the U.S. Food and Drug Administration (FDA) for broad use in assessing the risk of preterm birth. Adeza also markets and sells the E-tegrity(R) Test, an infertility-related test to assess receptivity of the uterus to embryo implantation in women with unexplained infertility. -0- Company: Adherex Technologies Inc. Ticker Symbol & Exchange: AMEX: ADH; TSX: AHX Investor Relations Contact: Melissa Matson Investor Relations Contact Phone: 919-484-8484 Web: www.adherex.com Date of Presentation: Nov. 8, 2005
Adherex Technologies Inc. is a biopharmaceutical company dedicated to the discovery and development of novel cancer therapeutics. We currently have multiple products in the clinical stage of development, including ADH-1 (Exherin(TM)), eniluracil and sodium thiosulfate (STS). ADH-1, our lead biotechnology compound, selectively targets N-cadherin, a protein present on certain tumor cells and established blood vessels that feed solid tumors. Eniluracil, an oral dihydropyrimidine dehydrogenase (DPD) inhibitor, was previously under development by GlaxoSmithKline for oncology indications. STS, a drug from our specialty pharmaceuticals pipeline, protects against the disabling hearing loss that can often result from treatment with platinum-based chemotherapy drugs. -0- Company: Aksys, Ltd. Ticker Symbol & Exchange: AKSY - NASDAQ Investor Relations Contact: Larry Birch Investor Relations Contact Phone: 847-229-2222 Web: www.aksys.com Date of Presentation: November 9, 2005 - 3:30 p.m. ET
Aksys was founded to develop dialysis products and services for patients suffering from kidney failure. Our lead product, the Aksys PHD(R) System, is designed to facilitate more frequent dialysis treatments. Studies have shown that increased dialysis frequency can improve the clinical outcomes of patients, as well as reduce morbidity and the associated high cost of patient care. Aksys' approach reflects the following: more frequent treatment is better than less frequent treatment; alternate sites, such as the patient's home, are preferable locations to perform chronic therapy; and an automated, user-friendly dialysis system will make home hemodialysis the preferred alternative therapy for many patients. Improved clinical outcomes in alternate settings also enable the patient to achieve increased quality of life and rehabilitation, the original goal of government-funded ESRD programs. -0- Company: Antares Pharma, Inc. Ticker Symbol & Exchange: AIS Investor Relations Contact: Steve Chizzik Investor Relations Contact Phone: 973.912.0980 Web: www.antarespharma.com Date of Presentation: 11/7/05
Antares Pharma is a specialized product development company with patented drug delivery systems combined with injectable device engineering capabilities. The Company's current technology platforms include its ATD(TM) (Advanced Transdermal Delivery) system, Easy Tec(TM) oral fast-melt technology, and subcutaneous injection technology platforms (Vibex(TM) disposable mini-needle injection device and Valeo(TM) and Vision(R) reusable needle-free injection devices). Antares is committed to leveraging its multiple drug delivery platforms to add value to existing drugs and to create new products and devices. The Company believes that its product pipeline addresses unmet medical needs by reducing side effect profiles, improving safety, increasing effectiveness, and improving patient compliance and convenience. The Company has active partnering programs with several pharmaceutical and distribution companies -0- Company: A.P. Pharma Ticker Symbol & Exchange: Nasdaq: APPA Investor Relations Contact: Zachary Bryant, Assistant VP Investor Relations Contact Phone: (310) 691-7100 Web: www.appharma.com Date of Presentation: Tuesday, November 8, 2005; 4:35 PM
A.P. Pharma is a specialty pharmaceutical company focused on the development of ethical (prescription) pharmaceuticals utilizing its proprietary polymer-based drug delivery systems. The Company's primary focus is the development and commercialization of its bioerodible injectable and implantable systems under the trade name Biochronomer(TM). Initial target areas of application for the Company's drug delivery technology include anti-nausea, pain management, inflammation and ophthalmic applications. The Company's product development programs are funded by the sale of common stock in June 2004, royalties from topical products currently marketed by pharmaceutical partners, proceeds from the divestitures of its cosmeceutical and analytical standards product lines and by fees it receives from collaborative partners. For further information visit the Company's Web site at www.appharma.com. -0- Company: Arena Pharmaceuticals Ticker Symbol & Exchange: NASDAQ: ARNA Investor Relations Contact: Susan Neath Investor Relations Contact Phone: 858-527-3486 Web: www.arenapharm.com Date of Presentation: November 8, 2005 at 10:30 a.m.
Arena is a biopharmaceutical company focusing on the development of orally available small molecule drugs for metabolic, cardiovascular, inflammatory and CNS diseases. Arena is developing compounds that act on G protein-coupled receptors. Arena's APD356 to treat obesity is in Phase 2b clinical trials, and APD125 to treat insomnia is scheduled to begin Phase 2 clinical trials by year-end. Additionally, Arena and Merck have a partner ship to treat atherosclerosis with an Arena-discovered product candidate currently in a Phase 1 clinical trial. Arena also has a collaboration with Ortho-McNeil, a Johnson & Johnson company, for type 2 diabetes. -0- Company: ArQule, Inc. Ticker Symbol & Exchange: NASDAQ: ARQL Investor Relations Contact: William B. Boni Investor Relations Contact Phone: 781-994-0614 Web: http://www.arqule.com Date of Presentation: November 7, 2005
ArQule, Inc., headquartered in Woburn, Mass., is a biotechnology company engaged in the research, development and commercialization of broadly effective cancer drugs with reduced toxicities compared to conventional chemotherapeutics. ArQule's cancer therapies are based on an innovative and proprietary scientific platform called Activated Checkpoint Therapy(SM) that applies a unique molecular biology approach supported by automated chemistries and intelligent drug design. The Company's lead drug candidate, ARQ 501, is partnered with Roche and in multiple Phase 1 clinical trials as monotherapy and in combination therapy with chemotherapeutic agents. A number of additional oncology research programs are in preclinical discovery and development. -0- Company: AVANT Immunotherapeutics, Inc. Ticker Symbol & Exchange: Nasdaq: AVAN Investor Relations Contact: Avery (Chip) W. Catlin Investor Relations Contact Phone: 781-433-3148 Web: www.avantimmune.com Date of Presentation: November 7, 2005 at 10:30 AM ET
AVANT Immunotherapeutics, Inc. discovers, develops and sells innovative vaccines and therapeutics that harness the human immune system to prevent and treat disease. AVANT has developed a broad, well-staged pipeline of products for large, high-value, under-served markets. These include our partner GlaxoSmithKline's oral rotavirus vaccine, Rotarix(R), which GSK is launching worldwide, a treatment to reduce complement-mediated damage associated with cardiac bypass surgery and a novel vaccine for cholesterol management. AVANT has assembled technologies that enable the creation of rapid-protecting, single-dose, oral vaccines that remain stable without refrigeration for application in four areas: biodefense, travelers' vaccines, global health, and human food safety. -0- Company: BioBalance Corporation, The Ticker Symbol & Exchange: OTCBB: BBAL Investor Relations Contact: Stan Wunderlich Investor Relations Contact Phone: (800) 625-2236 Web: www.biobalancecorp.com Date of Presentation: Nov 9, 2005
The BioBalance Corporation is a specialty pharmaceutical company focused on innovative treatments for gastrointestinal disorders that are poorly addressed by current therapies. Our lead product, PROBACTRIX(R), is a patented strain of E.coli M17 that displaces pathogenic bacteria in the GI tract addressing what scientists now believe to be a potential root cause of many GI disorders. BioBalance is pursuing accelerated prescription drug approval for pouchitis, a frequent complication following bowel surgery for which no drugs are currently approved. The Company is restructuring as a pure pharmaceutical business, divesting its home healthcare operations to focus exclusively on BioBalance. -0- Company: BioLife Solutions, Inc. Ticker Symbol & Exchange: NASDAQ: OTCBB: BLFS Investor Relations Contact: Jill Bertotti (Allen & Caron) Investor Relations Contact Phone: (949) 474-4300 Web: www.BioLifeSolutions.com Date of Presentation: Nov. 9, 2005 @ 3:30pm
BioLife Solutions, Inc. develops, manufactures, and markets low temperature technologies for use in preserving and prolonging the viability of cellular and genetic material for use in cell therapy, tissue engineering and a host of other markets. The Company's patented HypoThermosol(R) and CryoStor(TM) platform technologies are used to provide preservation solutions which significantly enhance storage and transportation capabilities for sensitive biological products. These facilitating technologies extend cell, tissue and organ viability post-preservation, which could, in turn improve clinical outcomes for new and existing cell and tissue therapy applications. -0- Company: Caprius, Inc. Ticker Symbol & Exchange: CAPS.OB Investor Relations Contact: Beverly Tkaczenko Investor Relations Contact Phone: (201) 592-8838 Web: www.caprius.com Date of Presentation: Tuesday, November 8, 2005 - 3:30 PM
Caprius, Inc. is a manufacturer of proprietary equipment for the on-site disinfection and disposal of infectious medical waste through its subsidiary, M.C.M. Environmental Technologies, Inc. (MCM). The company's innovative SteriMed technology simultaneously shreds and disinfects solid and liquid regulated medical ("red bag") waste, reducing the volume by up to 90% and rendering it harmless for disposal as ordinary waste. The SteriMed units are economical, compact, efficient and convenient, as well as environmentally friendly. The MCM patented technology offers an alternative to hauling and incinerating medical waste. Industry analysts estimate the medical waste market to be approximately $3 billion in the US. -0- Company: Chelsea Therapeutics Ticker Symbol & Exchange: OTC BB: CHTP Investor Relations Contact: Kathryn McNeil Investor Relations Contact Phone: 718-788-2856 Web: www.chelseatherapeutics.com Date of Presentation: November 7, 2005
Chelsea Therapeutics is a biopharmaceutical development company that acquires and develops innovative products for the treatment of a variety of human diseases. Chelsea is currently developing a pipeline of low toxicity, novel antifolate compounds engineered have potent anti-inflammatory and anti-tumor activity to treat a range of immunological disorders. Early clinical data suggests that Chelsea's lead product candidate, CH-1054, may be a safe and effective treatment alternative to methotrexate for rheumatoid arthritis ("RA") and may have further applications for psoriasis, certain cancers and other immunological disorders. -0- Company: ChemGenex Pharmaceuticals Ticker Symbol & Exchange: NASDAQ:CXSP ASX:CXS Investor Relations Contact: Hershel Berry Investor Relations Contact Phone: 415 392 3385 Web: www.chemgenex.com Date of Presentation: November 8, 2005
ChemGenex Pharmaceuticals is a genomics-driven pharmaceutical development company dedicated to improving the lives of patients by developing novel therapeutics in the areas of oncology, obesity, diabetes and depression. By focusing on validated targets in diseases with genetic components, we seek to bring targeted therapeutics to market that address chronic diseases with high unmet medical need. Our clinical pipeline of cancer drugs, coupled with our partnered discovery and development programs in diabetes and depression, provide us with a solid foundation to meet these objectives. -0- Company: CombiMatrix Corporation Ticker Symbol & Exchange: CBMX Investor Relations Contact: Bret Undem Investor Relations Contact Phone: 425.493.2293 Web: www.combimatrix.com Date of Presentation: Nov. 9th
CombiMatrix Corporation is a biotechnology company headquartered near Seattle, Washington, USA, with a wholly owned subsidiary, CombiMatrix Molecular Diagnostics headquartered in Irvine, California. CombiMatrix's patented electrochemical manufacturing process utilizes standard semiconductor technology, proprietary software, and chemistry to build arrays of materials -- molecule by molecule. The company's CustomArray(TM) products are DNA microarrays, which have uses in pharmaceutical, diagnostic, biotech, and agrochemical industries as well as in research and government markets. The company also uses its technology in synergistic internal programs for diagnostics, drug development, and biodefense in addition to partnerships for nanomaterials development. -0- Company: Cord Blood America, Inc. Ticker Symbol & Exchange: CBAI OTC BB Investor Relations Contact: Laura Fitzpatrick Investor Relations Contact Phone: 310-432-4090 Web: www.cordblood-america.com Date of Presentation: November 8th
Cord Blood America, Inc. ("the Company") is the parent company of Cord Partners, Inc., which provides private cord blood stem cells storage services to families. The Company has achieved rapid growth in its first 2 years of operation, and expects to continue to experience growth as awareness of the cord blood industry grows. Cord Partners sells its service to expectant parents. Families elect to store stem cells from umbilical cord blood because these stem cells may be used to treat future illnesses in the donor child or other family members. At present, umbilical cord blood stem cells can be used to treat approximately 75 diseases, including various forms of leukemia and anemia, and other immune system disorders. -0- Company: Curon Medical, Inc. Ticker Symbol & Exchange: CURN Investor Relations Contact: RxCommunications Investor Relations Contact Phone: Melody Carey917-322-2571 Web: www.curonmedical.com Date of Presentation: November 9, 2005
Curon Medical, founded in 1997, develops, manufactures and markets innovative proprietary products that employ radiofrequency (RF) energy for the treatment of gastrointestinal disorders. The Company markets the Stretta(R) System for treatment of gastroesophageal reflux disease (GERD) and the Secca(R) System for treatment of bowel incontinence. Both systems consist of a radiofrequency energy generator and single-use energy delivery devices. The Stretta(R) System received U.S. Food and Drug Administration clearance in April 2000 for the 14-minute RF Treatment for GERD. The Secca(R) System, which received clearance from the FDA in March 2002, enables the 20-minute RF Treatment for Bowel Incontinence. Webcast of presentation can be accessed at http://www.wsw.com/webcast/rrshq7/curn/ -0- Company: CytRx Corporation Ticker Symbol & Exchange: Nasdaq: CYTR Investor Relations Contact: Jody Cain, Senior Vice Preside Investor Relations Contact Phone: (310) 691-7100 Web: www.cytrx.com Date of Presentation: Tuesday, November 8, 2005; 9:45 AM
CytRx Corp. is a biopharmaceutical research and development company engaged in the development of products, primarily in the area of small molecules and ribonucleic acid interference (RNAi), in a variety of therapeutic categories. The Company owns three clinical-stage compounds based on its small molecule "molecular chaperone" co-induction technology, as well as a targeted library of 500 small molecule drug candidates that may be used to screen for new drug candidates. CytRx initiated a Phase II clinical trial with its lead small molecule product candidate arimoclomol for the treatment of amyotrophic lateral sclerosis (ALS). Arimoclomol received Orphan Drug and Fast Track designation from the U.S. FDA. CytRx has also licensed exclusive worldwide commercial rights to a novel DNA-based HIV vaccine technology, which has demonstrated positive interim Phase I clinical trial results. -0- Company: Discovery Laboratories, Inc. Ticker Symbol & Exchange: DSCO Investor Relations Contact: Lisa Caperelli Investor Relations Contact Phone: 215-488-9413 Web: www.discoverylabs.com Date of Presentation: 11/7/05
Discovery Labs is a biotechnology company developing its proprietary precision-engineered lung surfactant technology (which mimics the function of human lung surfactant) as Surfactant Replacement Therapies for respiratory diseases. Surfactants are produced naturally in the lungs and are essential for breathing. Discovery believes that through its technology, pulmonary surfactants have the potential, for the first time, to address respiratory diseases where there are few or no approved therapies available. Surfaxin(R), Discovery's lead product, has received an Approvable Letter from the FDA and is under review by the EMEA, for the prevention of Respiratory Distress Syndrome in premature infants. -0- Company: EntreMed, Inc. Ticker Symbol & Exchange: ENMD Investor Relations Contact: Ginny Dunn Investor Relations Contact Phone: 240-864-2643 Web: www.entremed.com Date of Presentation: Tuesday, November 8, 2005
EntreMed, Inc. is a clinical-stage pharmaceutical company focused on developing the next generation of multi-mechanism oncology and anti-inflammatory drugs that target disease cells directly and the blood vessels that nourish them. EntreMed is focused on developing drugs that are safe and convenient, and provide the potential for improved patient outcomes. Panzem(R) (2-methoxyestradiol or 2ME2), the Company's lead drug candidate, is currently in clinical trials for cancer, as well as in preclinical development for non-oncology indications, including rheumatoid arthritis. The Company's goal is to develop and commercialize new compounds based on the Company's expertise in the science of angiogenesis, cell cycle regulation and inflammation -- processes vital to the treatment of cancer and other diseases. -0- Company: Evotec AG Ticker Symbol & Exchange: EVT Investor Relations Contact: Anne Hennecke Investor Relations Contact Phone: +49-40-56081-286 Web: www.evotec.com Date of Presentation: 9 November 2005
Evotec is a leader in the discovery and development of novel small molecule drugs. Both through its own discovery programmes and through contract research partnerships, the Company is providing high quality research results to its partners in the pharmaceutical and biotechnology industry. In proprietary projects, Evotec specialises in finding new treatments for CNS diseases. Its lead compound, EVT 201, is in clinical phase I for the treatment of insomnia. In addition, the Company has a number of products in late stage pre-clinical development, the most advanced of which, EVT 101 for the treatment of Alzheimer's disease, is expected to enter clinical trials later this year. In contract research, Evotec provides innovative solutions from target to clinic through an unmatched range of capabilities, incl. early stage assay development/screening through to medicinal chemistry/manufacturing. -0- Company: GTC Biotherapeutics Ticker Symbol & Exchange: GTCB NASDAQ Investor Relations Contact: Thomas Newberry Investor Relations Contact Phone: 508-370-5374 Web: www.gtc-bio.com Date of Presentation: November 7, 2005 at 12:20 pm
GTC Biotherapeutics is a leader in the development, production, and commercialization of therapeutic proteins through transgenic animal technology. GTC currently has five products in its internal pipeline and a portfolio of external program production opportunities. GTC's lead program is ATryn(R), its recombinant form of human antithrombin. A Market Authorization Application is under review by the European Medicines Agency for the use of ATryn(R) in patients with a hereditary antithrombin deficiency. In its external programs, GTC's technology is used to develop transgenic production of its partners' proprietary products, including both large-volume protein therapeutics as well as products that are difficult to produce in significant quantities from conventional recombinant production systems. -0- Company: Halozyme Therapeutics Ticker Symbol & Exchange: AMEX:HTI Investor Relations Contact: Don Markley, Vice President Investor Relations Contact Phone: (310) 691-7100 Web: www.halozyme.com Date of Presentation: Tuesday, November 8, 2005; 9:25 AM
Halozyme is a biopharmaceutical company dedicated to developing and commercializing recombinant human enzymes for the infertility, ophthalmology, and oncology communities. The company's portfolio of products under development is based on intellectual property covering the family of human enzymes known as hyaluronidases. Halozyme's recombinant human enzymes may replace current animal slaughterhouse-derived enzymes that carry potential risks of animal pathogen transmission and immunogenicity. The versatility of the first enzyme, rHuPH20, enables Halozyme to develop the product as a medical device, drug enhancement agent, and therapeutic biologic. -0- Company: Hana Biosciences, Inc. Ticker Symbol & Exchange: AMEX: HBX Investor Relations Contact: Russell Skibsted Investor Relations Contact Phone: 650-588-6464 Web: www.hanabiosciences.com Date of Presentation: November 8, 2005, 9:45AM, Holmes II
Hana Biosciences (AMEX: HBX) acquires, develops, and commercializes innovative products to advance cancer care. Product pipeline includes: (1) Talotrexin (PT-523), a novel nonpolyglutamatable antifolate drug which has demonstrated enhanced antitumor activity in a broad spectrum of cancers by targeting DHFR to prevent DNA synthesis and inhibit tumor growth in Ph I/II clinical trials in NSCLC, ALL, and solid tumors;(2) Zensana(TM) (ondansetron oral spray), a novel, proprietary oral spray formulation of ondansetron that uses the highly-absorptive surfaces of the oral mucosa to deliver drug directly into the blood stream to prevent chemotherapy-induced nausea and vomiting being developed under 505(b)(2) registration for 2007 launch; and(3) IPdR, a novel, orally available, thymidine analogue and prodrug for IUdR, in Ph I clinical trials in colorectal, liver, gastric, and pancreatic cancers -0- Company: Insmed Incorporated Ticker Symbol & Exchange: INSM Investor Relations Contact: Baxter Phillips, III Investor Relations Contact Phone: 804.565.3041 Web: www.insmed.com Date of Presentation: November 7, 2005
Insmed is a biopharmaceutical company focused on the discovery and development of drug candidates for the treatment of metabolic diseases and endocrine disorders with unmet medical needs. -0- Company: INYX, INC. Ticker Symbol & Exchange: IYXI: OTCBB Investor Relations Contact: Jay M. Green, Executive VP Investor Relations Contact Phone: 212-838-1111 Web: www.inyxinc.com Date of Presentation: November 7, 2005
Inyx, Inc. is a specialty pharmaceutical company with niche drug delivery technologies and products for the treatment of respiratory, allergy, dermatological, topical and cardiovascular conditions. Inyx focuses its expertise on both prescription and over-the-counter pharmaceutical products, and provides specialty pharmaceutical development and production consulting services. In addition, Inyx is developing its own proprietary products to be marketed by selected clients and strategic partners. The company's operations are conducted through several wholly owned subsidiaries: Inyx USA, Ltd., based in Manati, Puerto Rico; Inyx Pharma Limited, near Manchester, England; Inyx Europe Limited, also near Manchester; Inyx Canada, Inc. in Toronto; and Exaeris, Inc., through which Inyx's strategic marketing collaborations are conducted. Inyx, Inc.'s corporate offices are in New York City. -0- Company: Isotechnika Inc. Ticker Symbol & Exchange: ISA:TSX Investor Relations Contact: Stephanie Gillis-Paulgaard Investor Relations Contact Phone: 780-487-1600 extension 243 Web: www.isotechnika.com Date of Presentation: November 7th
Isotechnika Inc. is an international biopharmaceutical company headquartered in Edmonton, Alberta, Canada. Drawing upon its expertise in medicinal chemistry and immunology, the Company is focused on the discovery and development of novel immunosuppressive therapeutics that are safer than currently available treatments. Isotechnika's lead compound, ISA247 is an immunosuppressant currently in a Canadian Phase III human clinical trial for the treatment of moderate to severe psoriasis. In addition, a Phase IIb kidney transplant trial with ISA247 will commence by the end of 2005. The Company also has two additional immunosuppressive compounds in its drug pipeline, TAFA93 and TKB662 which are in Phase I and pre-clinical respectively. -0- Company: Lipid Sciences, Inc. Ticker Symbol & Exchange: LIPD, Nasdaq Investor Relations Contact: Deborah S. Lorenz Investor Relations Contact Phone: 925-249-4031 Web: www.lipidsciences.com Date of Presentation: November 8, 2005
Lipid Sciences is a development-stage biotechnology company engaged in researching and developing products and processes to treat major medical indications, in which lipids (fat components) play a key role. The HDL Therapy platform (selective HDL delipidation and HDL mimetic peptides) focuses on reversing plaque build-up in the vascular system and coronary arteries thereby reducing acute coronary events. The Viral Immunotherapy platform focuses on removing lipid coatings from lipid-enveloped viruses, through delipidation technology, to stimulate the body's immune system to fight disease. Conditions that could be impacted by this technology include HIV, Hepatitis B and C, West Nile, SARS and influenza. -0- Company: MaxCyte, Inc. Investor Relations Contact: Ronald Holtz, CFO Investor Relations Contact Phone: 301-944-1624 Web: www.maxcyte.com Date of Presentation: November 8, 2005 at 12:40 PM EST
MaxCyte Inc. is a clinical stage company developing cell-based therapeutics primarily in the areas of oncology and regenerative medicine. MaxCyte's pipeline includes one product in Phase I/II clinical trials for the treatment of Chronic Lymphocytic Leukemia (CLL) and several preclinical candidates to treat a variety of diseases with unmet needs. The company also offers its unparalleled, customizable flow based cell loading technology to partners who take advantage of its advanced capabilities for cell-based therapeutic development and biotherapeutic (viral vector) manufacturing through licensing relationships. Partners are currently working to develop therapeutics for pulmonary, cardiovascular and infectious disease, cancer and regenerative medicine. -0- Company: MEDICURE INC Ticker Symbol & Exchange: Amex: MCU & TSX: MPH Investor Relations Contact: HOGAN MULLALLY Investor Relations Contact Phone: 204-487-7412 Web: www.medicure.com Date of Presentation: Nov. 8, 2005
Medicure Inc. is a cardiovascular drug discovery and development Company focused on developing effective therapeutics for unmet needs in the field of cardiovascular medicine, the largest pharmaceutical market sector. The Company's solid position in this field is supported by the following attributes -- Cardiovascular focused pipeline: a global market of over US $70 billion -- Two drugs - MC-1 & MC-4232 - in advanced clinical development -- Three positive Phase II trials completed -- Unique products addressing major markets not adequately served by existing drugs -- Dual action antithrombotic, MC-45308, in preclinical testing Medicure also has a medicinal chemistry based Drug Discovery program focused on discovery and advancement of novel small molecule, anti-ischemics and anti-thrombotics towards human clinical studies. -0- Company: MethylGene Inc. Ticker Symbol & Exchange: TSX : MYG Investor Relations Contact: Andrea Gilpin, Ph.D. Investor Relations Contact Phone: 514-337-3333 ext 416 Web: www.methylgene.com Date of Presentation: November 8, 2005
MethylGene is a biopharmaceutical specializing in cancer, antibiotic resistance, and other diseases such as diabetes, Huntington's, antifungals and inflammation. We currently have two compounds in human clinical trials: MGCD0103 and MG98. We have successfully partnered with Taiho Pharmaceutical, MGI Pharma, Merck and EnVivo Pharmaceuticals. MethylGene's in-house medicinal chemistry group synthesizes compounds that specifically target enzymes involved in certain diseases such as cancer. The ability to synthesize specific compounds allows MethylGene to target diseased cells leaving healthy cells untouched. This is in contrast to other approaches such as chemotherapy or radiation therapy in which both healthy and diseased cells are affected causing unnecessary side effects. Our strength is in our ability to discover, to develop, and deliver target-specific drugs. -0- Company: MicroIslet Inc. Ticker Symbol & Exchange: Amex: MII Investor Relations Contact: Bill Kachioff Investor Relations Contact Phone: 858-657-0287 Web: www.microislet.com Date of Presentation: 11/8/05
MicroIslet is a biotechnology company engaged in the research, development, and commercialization of patented technologies in the field of transplantation therapy for people with insulin-dependent diabetes. MicroIslet's patented islet transplantation technology includes methods for isolating, culturing, cryopreservation, and immuno-protection (microencapsulation) of islet cells. MicroIslet is working to develop and commercialize a first product, called MicroIslet-Px(TM), a microencapsulated porcine islet cell suspension that will be used for transplantation in patients with insulin-dependent diabetes. Additional information about MicroIslet can be found at www.microislet.com. -0- Company: Neoprobe Corporation Ticker Symbol & Exchange: NEOP (OTCBB) Investor Relations Contact: Brent Larson Investor Relations Contact Phone: 614.793.7500 x133 Web: www.neoprobe.com Date of Presentation: November 8, 2005 (1:00p.m.)
Neoprobe is a biomedical company focused on developing and commercializing innovative products that enhance patient care and improve patient outcome. Neoprobe currently markets the neo2000(R) line of gamma detection systems that are widely used by cancer surgeons and is commercializing the Quantix(R) line of blood flow measurement products. Neoprobe holds significant interests in the development of related biomedical systems and radiopharmaceutical agents including Lymphoseek(TM) and RIGScan(R) CR. Neoprobe's subsidiary, CIRA Biosciences, Inc., is also advancing a patient-specific cellular therapy technology platform called ACT. Neoprobe's strategy is to deliver superior growth and shareholder return by maximizing its strong position in gamma detection technologies and diversifying into new, synergistic biomedical markets through continued investment and selective acquisitions. -0- Company: NeuroHealing Pharmaceuticals, Inc. Investor Relations Contact: Daniel Katzman Investor Relations Contact Phone: 617 331-4111 Web: www.neurohealing.com Date of Presentation: November 8, 2005
NeuroHealing is a private, clinical stage company developing therapeutics to improve the functional outcome of post-acute neurorehabilitation patients, including disorders such as traumatic brain injury, stroke, Parkinson's disease and other motor neuron diseases. NeuroHealing is developing three reprofiled drug candidates, each with early evidence of clinical efficacy, extensive human safety data and featuring formulation and drug delivery strategies:NH001 is designed to accelerate the recovery and improve the functional outcome of patients from a coma, vegetative or minimally conscious state following a traumatic brain injury. NH004 is a novel treatment for sialorrhea (drooling), an embarrassing complication in Parkinson's, Cerebral Palsy and other neurological conditions. NH02D is designed to improve the rehabilitation outcomes of stroke patients. -0- Company: NovaDel Pharma Ticker Symbol & Exchange: AMEX NVD Investor Relations Contact: Michael Spicer Investor Relations Contact Phone: Michael Spicer, 908.782.3431 X2550 Web: www.novadel.com Date of Presentation: November 7, 2005
NovaDel Pharma Inc. is a specialty pharmaceutical company that is developing a novel drug-delivery system for both prescription and over-the-counter therapeutics. The Company's proprietary technology uses an oral spray to rapidly deliver drugs into the systemic circulation. The technology can be applied to a variety of drugs in the Rx, OTC and veterinary therapeutic areas. Drugs administered in a spray form to the oral mucosa have the potential for a) faster onset of action, b) improved safety profile and c) enhanced patient compliance. -0- Company: OrthoLogic Corp. Ticker Symbol & Exchange: OLGC Investor Relations Contact: Sherry Sturman Investor Relations Contact Phone: 602-286-5436 Web: www.orthologic.com Date of Presentation: Monday, November 7, 2005 8:00 a.m.
OrthoLogic is a biotechnology company focused on the development and commercialization of the novel synthetic peptide Chrysalin(R) (TP508) in three lead indications, all of which represent areas of significant unmet medical need - fracture repair, diabetic foot ulcer healing and cartilage defect repair. Based on the Company's pioneering scientific research of the natural healing cascade, OrthoLogic has become the leading company focused on tissue and bone repair. OrthoLogic is committed to developing a pipeline of novel peptides and other molecules aimed at helping patients with unmet medical needs and under-served conditions. The Company maintains exclusive worldwide rights for Chrysalin. -0- Company: OXiGENE, Inc. Ticker Symbol & Exchange: Nasdaq/XSSE: OXGN Investor Relations Contact: Susan Hager Investor Relations Contact Phone: 781-547-5900 Web: www.oxigene.com Date of Presentation: Nov. 8, 2005
OXiGENE is an emerging pharmaceutical company developing novel small-molecule therapeutics to treat cancer and eye diseases. The Company's major focus is the clinical advancement of drug candidates that selectively disrupt abnormal blood vessels associated with solid tumor progression and visual impairment. OXiGENE is dedicated to leveraging its intellectual property position and therapeutic development expertise to bring life saving and enhancing medicines to patients. -0- Company: PAION Ticker Symbol & Exchange: PA8 Investor Relations Contact: Dr. Peer Nils Schroder Investor Relations Contact Phone: +49-241-4453-152 Web: www.paion.de Date of Presentation: 7.11.2005, 10.10 a.m.
PAION, a biopharmaceutical company based in Aachen, Germany, aims to become a leader in developing and commercialising innovative drugs for the treatment of stroke and other thrombotic diseases for which there is a substantial unmet medical need. PAION intends to build an integrated drug portfolio by exploiting its expertise in identifying compounds, licensing or otherwise acquiring them and advancing them through the clinical development and regulatory approval process. PAION's lead product Desmoteplase for the treatment of acute ischaemic stroke is currently in Phase III. During the first half-year 2005, PAION employed on average 59 people. -0- Company: Panacos Pharmaceuticals, Inc. Ticker Symbol & Exchange: PANC (Nasdaq) Investor Relations Contact: Jill Smith Investor Relations Contact Phone: 240.631.1395 x-1250 Web: http://www.panacos.com Date of Presentation: November 7, 2005
Panacos is developing the next generation of anti-infective products through discovery and development of small molecule oral drugs for the treatment of HIV and other major human viral diseases. Panacos' proprietary discovery technologies and lead therapeutic candidate, PA-457, focus on novel targets in the virus life cycle, including virus maturation and virus fusion. -0- Company: PharmaFrontiers Corp. Ticker Symbol & Exchange: PFTR.OB Investor Relations Contact: C. W. "Bill" Rouse, CFO Investor Relations Contact Phone: 281-775-0608 Web: www.pharmafrontierscorp.com Date of Presentation: November 9, 2005 (9:45 AM) Kennedy II
PharmaFrontiers' strategy is to develop and commercialize cell therapies to treat several major disease areas such as cardiac and pancreatic conditions and Multiple Sclerosis. PharmaFrontiers owns patented and proprietary individualized cell therapies that are in FDA Phase I/II human dose ranging clinical trials to evaluate their safety and effectiveness in treating MS. The company also holds the exclusive worldwide license from the University of Chicago, through its prime contractor relationship with Argonne National Laboratory, for patents relating to the use of adult pluripotent stem cells derived from patients' own circulating blood. -0- Company: Protein Polymer Technologies, Inc. Ticker Symbol & Exchange: OTC BB: PPTI Investor Relations Contact: Erin Davis Investor Relations Contact Phone: (858) 558-6064 x 120 Web: www.ppti.com Date of Presentation: Wednesday, November 9, 2005
Protein Polymer Technologies, Inc. is a biotechnology company that discovers and develops innovative therapeutic devices to improve medical and surgical outcomes. The Company focuses on developing technology and products to be used for soft tissue augmentation, tissue adhesives and sealants, wound healing support and drug delivery devices. Protein Polymer Technologies' proprietary protein-based biomaterials are uniquely tailored to optimize clinical performance and contain no human or animal components that could potentially transmit or cause disease. The company is headquartered in San Diego, California. For additional information about the company, please visit www.ppti.com. -0- Company: Regeneration Technologies, Inc. Ticker Symbol & Exchange: RTIX, NASDAQ Investor Relations Contact: Wendy Crites Wacker Investor Relations Contact Phone: (386) 418-8888 Web: www.rtix.com Date of Presentation: November 8, 2005
RTI processes allograft and xenograft tissue into shaped implants for use in orthopedic, cardiovascular and other surgeries with a commitment to science, safety and innovation. RTI also holds the patents on BioCleanse(R), the only proven tissue sterilization process validated to eliminate viruses, bacteria, fungi and spores from tissue without impacting the structural or biomechanical integrity of the tissue. The company has distributed more than 600,000 allograft implants sterilized with the BioCleanse process with zero incidence of infection. RTI is accredited by the American Association of Tissue Banks and was named a 2004 Technology Pioneer by the World Economic Forum. -0- Company: Santarus Inc. Ticker Symbol & Exchange: Nasdaq: SNTS Investor Relations Contact: Jody Cain, Senior VP Investor Relations Contact Phone: (310) 691-7100 Web: www.santarus.com Date of Presentation: Wed., November 9, 2005, 9:25 AM
Santarus, Inc. is a specialty pharmaceutical company focused on acquiring, developing and commercializing proprietary products to enhance the quality of life for patients with gastrointestinal diseases and disorders. The company's current products are immediate-release formulations of omeprazole, a widely prescribed proton pump inhibitor (PPI). The company launched its first product, ZEGERID(R) Powder for Oral Suspension 20 mg, in October 2004 and launched ZEGERID Powder for Oral Suspension 40 mg in February 2005. The company submitted a New Drug Application (NDA) for ZEGERID Capsules to the U.S. Food and Drug Administration (FDA) in April 2005 and submitted an NDA for ZEGERID Chewable Tablets to the FDA in May 2005. More information about Santarus is available on the company's Web site at www.santarus.com. -0- Company: Solexa Inc. Ticker Symbol & Exchange: Nasdaq: SLXA Investor Relations Contact: Jody Cain, Senior VP Investor Relations Contact Phone: (310) 691-7100 Web: www.solexa.com Date of Presentation: Tuesday, November 8, 2005; 4:35 PM
Solexa is developing and preparing to commercialize a new genetic analysis instrument system which will be used to perform a range of analyses including whole genome resequencing, gene expression analysis and micro-RNA analysis. Solexa scientists have sequenced a human bacterial artificial chromosome, an important milestone demonstrating that its technology can be applied to resequence human DNA. Solexa expects its first-generation technology to generate over a billion bases of DNA sequence per run and to enable whole genome resequencing below $100,000 per sample, making it the first platform to reach this important milestone. Solexa's longer-term goal is to reduce the cost of human resequencing to a few thousand dollars for use in a wide range of applications from basic research through clinical diagnostics. Solexa expects to introduce its first instrument system by the end of 2005. -0- Company: Spectranetics Corporation Ticker Symbol & Exchange: Nasdaq: SPNC Investor Relations Contact: Don Markley, Vice President Investor Relations Contact Phone: (310) 691-7100 Web: www.cytrx.com Date of Presentation: Wed., November 9, 2005; 11:55 AM
Spectranetics is a medical device company that develops, manufactures and markets single-use medical devices used in minimally invasive surgical procedures within the cardiovascular system in conjunction with its proprietary excimer laser system. Its CVX-300(R) excimer laser is the only system approved by the FDA for multiple cardiovascular procedures, including coronary atherectomy, and the removal of problematic pacemaker and defibrillator leads. Nearly all of the company's FDA-approved and investigational applications have received Communautes Europeennes (CE) mark registration for marketing within Europe. In April 2004 Spectranetics obtained 510(k) clearance from the FDA for the laser-based treatment of patients suffering from total occlusions (blockages) in their leg arteries that are not crossable with a guide wire. -0- Company: StemCells, Inc. Ticker Symbol & Exchange: Nasdaq: STEM Investor Relations Contact: Rodney Young, CFO Investor Relations Contact Phone: 650 475 3100 ext 105 Web: www.stemcellsinc.com Date of Presentation: November 7, 2005
StemCells, Inc. is developing stem cell therapeutics using adult stem cell technology. The Company to date has discovered the human neural stem cell (HuCNS-SC(TM)) and candidate liver and pancreatic stem cells. StemCells has over 40 issued US patents in the neural stem cell field. StemCells' initial target indications are lysosomal storage diseases that affect the CNS, and in October 2005, the FDA cleared the Company to begin a Phase I clinical trial in Batten disease. This will be the first FDA-approved trial to transplant human neural stem cells. StemCells is continuing preclinical evaluation of HuCNS-SC as a treatment for spinal cord injury, stroke and other CNS indications. -0- Company: TRANSGENE Ticker Symbol & Exchange: TRGNY (Pink Sheets) Investor Relations Contact: Philippe Poncet Investor Relations Contact Phone: + 33 3 88 27 91 21 Web: www.transgene.fr Date of Presentation: November 8, 2005
Transgene is a France-based biopharmaceutical company dedicated to the development of therapeutic vaccines and immunotherapeutic products in oncology and infectious diseases. The company has three compounds in Phase II trials and one compound in Phase I study. Transgene has bio-manufacturing capacities for the production of viral-based vectors (adenovirus and vaccinia virus) and technologies available for out-licensing.
By developing expertise in applied research, clinical and production capabilities (2800 sq. meter GMP production facility) while maintaining broad intellectual property of over 200 patent families, Transgene is uniquely poised to advance cancer and infectious diseases therapies through both in-house and partnered development. -0- Company: Transition Therapeutics Ticker Symbol & Exchange: TTH Investor Relations Contact: Soraya Centeno Investor Relations Contact Phone: 416 260 7770 ext. 243 Web: www.transitiontherapeutics.com Date of Presentation: November 8th at 11:55am
Transition Therapeutics is a product-focused biopharmaceutical company, developing novel therapeutics for disease indications with large markets. The company's strategy is to develop multiple products in parallel, thereby leveraging its internal resources and expertise across many opportunities. Transition's development focus is to concentrate on preclinical products that can be quickly advanced to Phase II trials for large disease indications. Transition is currently developing five products that target diabetes (Type I and II), multiple sclerosis, hepatitis C and Alzheimer's disease (Alzheimer's disease-modifying therapy). Transition's robust product pipeline and recent licensing agreement with leading diabetes company Novo Nordisk demonstrate the Company's ability to develop multiple clinical programs in parallel and attract large pharma partnerships. -0- Company: VioQuest Pharmaceuticals Ticker Symbol & Exchange: OTCBB: VQPH Investor Relations Contact: Amanda Watkins Investor Relations Contact Phone: 212-825-3210 Web: www.vioquestpharm.com Date of Presentation: November 9, @ 10:10 AM
VioQuest Pharmaceuticals, Inc. acquires and develops targeted late preclinical and early clinical stage therapies with unique mechanisms of action for oncology, viral and autoimmune disorders. The Company is developing two novel anti-cancer agents VQD-001 and VQD-002 for the treatment of melanoma, myeloma, lymphoma; and breast, ovarian, pancreatic, colorectal cancers, respectively. VioQuest's subsidiary, Chiral Quest, Inc., a pioneer in asymmetric synthesis, offers proprietary chiral catalysts and synthesis expertise for creating important chiral intermediates and products, which improves the safety, efficacy and manufacturing efficiency of pharmaceutical products. Chiral Quest provides products and services to twelve of the top eighteen pharmaceutical companies worldwide. -0- Company: ZIOPHARM Oncology Ticker Symbol & Exchange: ZIOP.OB Investor Relations Contact: Kelly Luethje & Suzanne McKenna Investor Relations Contact Phone: 617-259-1975/ 646-214-0703 Web: www.ziopharm.com Date of Presentation: 8:40-9:00 am
ZIOPHARM Oncology, Inc. is a biopharmaceutical company seeking to acquire, develop and commercialize a diverse, risk-sensitive portfolio of in-licensed cancer drugs that address unmet medical needs. Currently, the Company is in U.S. phase I studies for its two product candidates, ZIO-101 and ZIO-201. -0- Company: ZymoGenetics Ticker Symbol & Exchange: NASDAQ: ZGEN Investor Relations Contact: John Calhoun Investor Relations Contact Phone: 206-442-6744 Web: www.zymogenetics.com Date of Presentation: November 7, 2005
ZymoGenetics is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutic proteins for the prevention or treatment of human diseases. The Company is developing a diverse pipeline of potential proprietary product candidates that are moving into and through clinical development. These span a wide array of clinical opportunities that include bleeding, autoimmune diseases and cancer. ZymoGenetics intends to commercialize these product candidates through internal development, collaborations with partners, and out-licensing of patents from its extensive patent portfolio. For further information, visit www.zymogenetics.com.
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Below are profiles from Techvest 7th Annual Healthcare Conference presenters. News releases, web cast advisories, and photos are available at http://home.businesswire.com/portal/site/bwges-techvest-health-05/.
Business Wire is the official news wire service for the Techvest 7th Annual Healthcare Conference. -0- Company: Active Biotech AB Ticker Symbol & Exchange: ACTI.SE SEK Investor Relations Contact: Cecilia Hofvander Investor Relations Contact Phone: +46 46 19 11 22 or +46 701 89 11 22 Web: www.activebiotech.com Date of Presentation: Nov 8
Active Biotech AB is a biotechnology company focusing on research and development of pharmaceuticals. Active Biotech has a strong R&D portfolio with pipeline products focused on autoimmune/inflammatory diseases and cancer. Most advanced projects are laquinimod, an orally administered small molecule with unique immunomodulatory properties for the treatment of multiple sclerosis, as well as ANYARA for use in cancer immunotherapy with the primary indication non-small cell lung cancer. Further key projects in clinical development comprise the three orally administered compounds TASQ for prostate cancer 57-57 for SLE and RhuDex(R) for RA. -0- Company: Adeza Biomedical Ticker Symbol & Exchange: Nasdaq: ADZA Investor Relations Contact: Brandi Floberg Investor Relations Contact Phone: 310-691-7100 Web: www.adeza.com Date of Presentation: November 9, 2005 at 11:15 a.m. ET
Adeza designs, manufactures and markets innovative products for women's health. Adeza's initial focus is on reproductive healthcare, using its proprietary technologies to predict preterm birth and assess infertility. Adeza's principal product is a patented diagnostic test, FullTerm(TM) The Fetal Fibronectin Test, which utilizes a single-use, disposable cassette and is analyzed on Adeza's patented TLiIQ(R) System. This product is approved by the U.S. Food and Drug Administration (FDA) for broad use in assessing the risk of preterm birth. Adeza also markets and sells the E-tegrity(R) Test, an infertility-related test to assess receptivity of the uterus to embryo implantation in women with unexplained infertility. -0- Company: Adherex Technologies Inc. Ticker Symbol & Exchange: AMEX: ADH; TSX: AHX Investor Relations Contact: Melissa Matson Investor Relations Contact Phone: 919-484-8484 Web: www.adherex.com Date of Presentation: Nov. 8, 2005
Adherex Technologies Inc. is a biopharmaceutical company dedicated to the discovery and development of novel cancer therapeutics. We currently have multiple products in the clinical stage of development, including ADH-1 (Exherin(TM)), eniluracil and sodium thiosulfate (STS). ADH-1, our lead biotechnology compound, selectively targets N-cadherin, a protein present on certain tumor cells and established blood vessels that feed solid tumors. Eniluracil, an oral dihydropyrimidine dehydrogenase (DPD) inhibitor, was previously under development by GlaxoSmithKline for oncology indications. STS, a drug from our specialty pharmaceuticals pipeline, protects against the disabling hearing loss that can often result from treatment with platinum-based chemotherapy drugs. -0- Company: Aksys, Ltd. Ticker Symbol & Exchange: AKSY - NASDAQ Investor Relations Contact: Larry Birch Investor Relations Contact Phone: 847-229-2222 Web: www.aksys.com Date of Presentation: November 9, 2005 - 3:30 p.m. ET
Aksys was founded to develop dialysis products and services for patients suffering from kidney failure. Our lead product, the Aksys PHD(R) System, is designed to facilitate more frequent dialysis treatments. Studies have shown that increased dialysis frequency can improve the clinical outcomes of patients, as well as reduce morbidity and the associated high cost of patient care. Aksys' approach reflects the following: more frequent treatment is better than less frequent treatment; alternate sites, such as the patient's home, are preferable locations to perform chronic therapy; and an automated, user-friendly dialysis system will make home hemodialysis the preferred alternative therapy for many patients. Improved clinical outcomes in alternate settings also enable the patient to achieve increased quality of life and rehabilitation, the original goal of government-funded ESRD programs. -0- Company: Antares Pharma, Inc. Ticker Symbol & Exchange: AIS Investor Relations Contact: Steve Chizzik Investor Relations Contact Phone: 973.912.0980 Web: www.antarespharma.com Date of Presentation: 11/7/05
Antares Pharma is a specialized product development company with patented drug delivery systems combined with injectable device engineering capabilities. The Company's current technology platforms include its ATD(TM) (Advanced Transdermal Delivery) system, Easy Tec(TM) oral fast-melt technology, and subcutaneous injection technology platforms (Vibex(TM) disposable mini-needle injection device and Valeo(TM) and Vision(R) reusable needle-free injection devices). Antares is committed to leveraging its multiple drug delivery platforms to add value to existing drugs and to create new products and devices. The Company believes that its product pipeline addresses unmet medical needs by reducing side effect profiles, improving safety, increasing effectiveness, and improving patient compliance and convenience. The Company has active partnering programs with several pharmaceutical and distribution companies -0- Company: A.P. Pharma Ticker Symbol & Exchange: Nasdaq: APPA Investor Relations Contact: Zachary Bryant, Assistant VP Investor Relations Contact Phone: (310) 691-7100 Web: www.appharma.com Date of Presentation: Tuesday, November 8, 2005; 4:35 PM
A.P. Pharma is a specialty pharmaceutical company focused on the development of ethical (prescription) pharmaceuticals utilizing its proprietary polymer-based drug delivery systems. The Company's primary focus is the development and commercialization of its bioerodible injectable and implantable systems under the trade name Biochronomer(TM). Initial target areas of application for the Company's drug delivery technology include anti-nausea, pain management, inflammation and ophthalmic applications. The Company's product development programs are funded by the sale of common stock in June 2004, royalties from topical products currently marketed by pharmaceutical partners, proceeds from the divestitures of its cosmeceutical and analytical standards product lines and by fees it receives from collaborative partners. For further information visit the Company's Web site at www.appharma.com. -0- Company: Arena Pharmaceuticals Ticker Symbol & Exchange: NASDAQ: ARNA Investor Relations Contact: Susan Neath Investor Relations Contact Phone: 858-527-3486 Web: www.arenapharm.com Date of Presentation: November 8, 2005 at 10:30 a.m.
Arena is a biopharmaceutical company focusing on the development of orally available small molecule drugs for metabolic, cardiovascular, inflammatory and CNS diseases. Arena is developing compounds that act on G protein-coupled receptors. Arena's APD356 to treat obesity is in Phase 2b clinical trials, and APD125 to treat insomnia is scheduled to begin Phase 2 clinical trials by year-end. Additionally, Arena and Merck have a partner ship to treat atherosclerosis with an Arena-discovered product candidate currently in a Phase 1 clinical trial. Arena also has a collaboration with Ortho-McNeil, a Johnson & Johnson company, for type 2 diabetes. -0- Company: ArQule, Inc. Ticker Symbol & Exchange: NASDAQ: ARQL Investor Relations Contact: William B. Boni Investor Relations Contact Phone: 781-994-0614 Web: http://www.arqule.com Date of Presentation: November 7, 2005
ArQule, Inc., headquartered in Woburn, Mass., is a biotechnology company engaged in the research, development and commercialization of broadly effective cancer drugs with reduced toxicities compared to conventional chemotherapeutics. ArQule's cancer therapies are based on an innovative and proprietary scientific platform called Activated Checkpoint Therapy(SM) that applies a unique molecular biology approach supported by automated chemistries and intelligent drug design. The Company's lead drug candidate, ARQ 501, is partnered with Roche and in multiple Phase 1 clinical trials as monotherapy and in combination therapy with chemotherapeutic agents. A number of additional oncology research programs are in preclinical discovery and development. -0- Company: AVANT Immunotherapeutics, Inc. Ticker Symbol & Exchange: Nasdaq: AVAN Investor Relations Contact: Avery (Chip) W. Catlin Investor Relations Contact Phone: 781-433-3148 Web: www.avantimmune.com Date of Presentation: November 7, 2005 at 10:30 AM ET
AVANT Immunotherapeutics, Inc. discovers, develops and sells innovative vaccines and therapeutics that harness the human immune system to prevent and treat disease. AVANT has developed a broad, well-staged pipeline of products for large, high-value, under-served markets. These include our partner GlaxoSmithKline's oral rotavirus vaccine, Rotarix(R), which GSK is launching worldwide, a treatment to reduce complement-mediated damage associated with cardiac bypass surgery and a novel vaccine for cholesterol management. AVANT has assembled technologies that enable the creation of rapid-protecting, single-dose, oral vaccines that remain stable without refrigeration for application in four areas: biodefense, travelers' vaccines, global health, and human food safety. -0- Company: BioBalance Corporation, The Ticker Symbol & Exchange: OTCBB: BBAL Investor Relations Contact: Stan Wunderlich Investor Relations Contact Phone: (800) 625-2236 Web: www.biobalancecorp.com Date of Presentation: Nov 9, 2005
The BioBalance Corporation is a specialty pharmaceutical company focused on innovative treatments for gastrointestinal disorders that are poorly addressed by current therapies. Our lead product, PROBACTRIX(R), is a patented strain of E.coli M17 that displaces pathogenic bacteria in the GI tract addressing what scientists now believe to be a potential root cause of many GI disorders. BioBalance is pursuing accelerated prescription drug approval for pouchitis, a frequent complication following bowel surgery for which no drugs are currently approved. The Company is restructuring as a pure pharmaceutical business, divesting its home healthcare operations to focus exclusively on BioBalance. -0- Company: BioLife Solutions, Inc. Ticker Symbol & Exchange: NASDAQ: OTCBB: BLFS Investor Relations Contact: Jill Bertotti (Allen & Caron) Investor Relations Contact Phone: (949) 474-4300 Web: www.BioLifeSolutions.com Date of Presentation: Nov. 9, 2005 @ 3:30pm
BioLife Solutions, Inc. develops, manufactures, and markets low temperature technologies for use in preserving and prolonging the viability of cellular and genetic material for use in cell therapy, tissue engineering and a host of other markets. The Company's patented HypoThermosol(R) and CryoStor(TM) platform technologies are used to provide preservation solutions which significantly enhance storage and transportation capabilities for sensitive biological products. These facilitating technologies extend cell, tissue and organ viability post-preservation, which could, in turn improve clinical outcomes for new and existing cell and tissue therapy applications. -0- Company: Caprius, Inc. Ticker Symbol & Exchange: CAPS.OB Investor Relations Contact: Beverly Tkaczenko Investor Relations Contact Phone: (201) 592-8838 Web: www.caprius.com Date of Presentation: Tuesday, November 8, 2005 - 3:30 PM
Caprius, Inc. is a manufacturer of proprietary equipment for the on-site disinfection and disposal of infectious medical waste through its subsidiary, M.C.M. Environmental Technologies, Inc. (MCM). The company's innovative SteriMed technology simultaneously shreds and disinfects solid and liquid regulated medical ("red bag") waste, reducing the volume by up to 90% and rendering it harmless for disposal as ordinary waste. The SteriMed units are economical, compact, efficient and convenient, as well as environmentally friendly. The MCM patented technology offers an alternative to hauling and incinerating medical waste. Industry analysts estimate the medical waste market to be approximately $3 billion in the US. -0- Company: Chelsea Therapeutics Ticker Symbol & Exchange: OTC BB: CHTP Investor Relations Contact: Kathryn McNeil Investor Relations Contact Phone: 718-788-2856 Web: www.chelseatherapeutics.com Date of Presentation: November 7, 2005
Chelsea Therapeutics is a biopharmaceutical development company that acquires and develops innovative products for the treatment of a variety of human diseases. Chelsea is currently developing a pipeline of low toxicity, novel antifolate compounds engineered have potent anti-inflammatory and anti-tumor activity to treat a range of immunological disorders. Early clinical data suggests that Chelsea's lead product candidate, CH-1054, may be a safe and effective treatment alternative to methotrexate for rheumatoid arthritis ("RA") and may have further applications for psoriasis, certain cancers and other immunological disorders. -0- Company: ChemGenex Pharmaceuticals Ticker Symbol & Exchange: NASDAQ:CXSP ASX:CXS Investor Relations Contact: Hershel Berry Investor Relations Contact Phone: 415 392 3385 Web: www.chemgenex.com Date of Presentation: November 8, 2005
ChemGenex Pharmaceuticals is a genomics-driven pharmaceutical development company dedicated to improving the lives of patients by developing novel therapeutics in the areas of oncology, obesity, diabetes and depression. By focusing on validated targets in diseases with genetic components, we seek to bring targeted therapeutics to market that address chronic diseases with high unmet medical need. Our clinical pipeline of cancer drugs, coupled with our partnered discovery and development programs in diabetes and depression, provide us with a solid foundation to meet these objectives. -0- Company: CombiMatrix Corporation Ticker Symbol & Exchange: CBMX Investor Relations Contact: Bret Undem Investor Relations Contact Phone: 425.493.2293 Web: www.combimatrix.com Date of Presentation: Nov. 9th
CombiMatrix Corporation is a biotechnology company headquartered near Seattle, Washington, USA, with a wholly owned subsidiary, CombiMatrix Molecular Diagnostics headquartered in Irvine, California. CombiMatrix's patented electrochemical manufacturing process utilizes standard semiconductor technology, proprietary software, and chemistry to build arrays of materials -- molecule by molecule. The company's CustomArray(TM) products are DNA microarrays, which have uses in pharmaceutical, diagnostic, biotech, and agrochemical industries as well as in research and government markets. The company also uses its technology in synergistic internal programs for diagnostics, drug development, and biodefense in addition to partnerships for nanomaterials development. -0- Company: Cord Blood America, Inc. Ticker Symbol & Exchange: CBAI OTC BB Investor Relations Contact: Laura Fitzpatrick Investor Relations Contact Phone: 310-432-4090 Web: www.cordblood-america.com Date of Presentation: November 8th
Cord Blood America, Inc. ("the Company") is the parent company of Cord Partners, Inc., which provides private cord blood stem cells storage services to families. The Company has achieved rapid growth in its first 2 years of operation, and expects to continue to experience growth as awareness of the cord blood industry grows. Cord Partners sells its service to expectant parents. Families elect to store stem cells from umbilical cord blood because these stem cells may be used to treat future illnesses in the donor child or other family members. At present, umbilical cord blood stem cells can be used to treat approximately 75 diseases, including various forms of leukemia and anemia, and other immune system disorders. -0- Company: Curon Medical, Inc. Ticker Symbol & Exchange: CURN Investor Relations Contact: RxCommunications Investor Relations Contact Phone: Melody Carey917-322-2571 Web: www.curonmedical.com Date of Presentation: November 9, 2005
Curon Medical, founded in 1997, develops, manufactures and markets innovative proprietary products that employ radiofrequency (RF) energy for the treatment of gastrointestinal disorders. The Company markets the Stretta(R) System for treatment of gastroesophageal reflux disease (GERD) and the Secca(R) System for treatment of bowel incontinence. Both systems consist of a radiofrequency energy generator and single-use energy delivery devices. The Stretta(R) System received U.S. Food and Drug Administration clearance in April 2000 for the 14-minute RF Treatment for GERD. The Secca(R) System, which received clearance from the FDA in March 2002, enables the 20-minute RF Treatment for Bowel Incontinence. Webcast of presentation can be accessed at http://www.wsw.com/webcast/rrshq7/curn/ -0- Company: CytRx Corporation Ticker Symbol & Exchange: Nasdaq: CYTR Investor Relations Contact: Jody Cain, Senior Vice Preside Investor Relations Contact Phone: (310) 691-7100 Web: www.cytrx.com Date of Presentation: Tuesday, November 8, 2005; 9:45 AM
CytRx Corp. is a biopharmaceutical research and development company engaged in the development of products, primarily in the area of small molecules and ribonucleic acid interference (RNAi), in a variety of therapeutic categories. The Company owns three clinical-stage compounds based on its small molecule "molecular chaperone" co-induction technology, as well as a targeted library of 500 small molecule drug candidates that may be used to screen for new drug candidates. CytRx initiated a Phase II clinical trial with its lead small molecule product candidate arimoclomol for the treatment of amyotrophic lateral sclerosis (ALS). Arimoclomol received Orphan Drug and Fast Track designation from the U.S. FDA. CytRx has also licensed exclusive worldwide commercial rights to a novel DNA-based HIV vaccine technology, which has demonstrated positive interim Phase I clinical trial results. -0- Company: Discovery Laboratories, Inc. Ticker Symbol & Exchange: DSCO Investor Relations Contact: Lisa Caperelli Investor Relations Contact Phone: 215-488-9413 Web: www.discoverylabs.com Date of Presentation: 11/7/05
Discovery Labs is a biotechnology company developing its proprietary precision-engineered lung surfactant technology (which mimics the function of human lung surfactant) as Surfactant Replacement Therapies for respiratory diseases. Surfactants are produced naturally in the lungs and are essential for breathing. Discovery believes that through its technology, pulmonary surfactants have the potential, for the first time, to address respiratory diseases where there are few or no approved therapies available. Surfaxin(R), Discovery's lead product, has received an Approvable Letter from the FDA and is under review by the EMEA, for the prevention of Respiratory Distress Syndrome in premature infants. -0- Company: EntreMed, Inc. Ticker Symbol & Exchange: ENMD Investor Relations Contact: Ginny Dunn Investor Relations Contact Phone: 240-864-2643 Web: www.entremed.com Date of Presentation: Tuesday, November 8, 2005
EntreMed, Inc. is a clinical-stage pharmaceutical company focused on developing the next generation of multi-mechanism oncology and anti-inflammatory drugs that target disease cells directly and the blood vessels that nourish them. EntreMed is focused on developing drugs that are safe and convenient, and provide the potential for improved patient outcomes. Panzem(R) (2-methoxyestradiol or 2ME2), the Company's lead drug candidate, is currently in clinical trials for cancer, as well as in preclinical development for non-oncology indications, including rheumatoid arthritis. The Company's goal is to develop and commercialize new compounds based on the Company's expertise in the science of angiogenesis, cell cycle regulation and inflammation -- processes vital to the treatment of cancer and other diseases. -0- Company: Evotec AG Ticker Symbol & Exchange: EVT Investor Relations Contact: Anne Hennecke Investor Relations Contact Phone: +49-40-56081-286 Web: www.evotec.com Date of Presentation: 9 November 2005
Evotec is a leader in the discovery and development of novel small molecule drugs. Both through its own discovery programmes and through contract research partnerships, the Company is providing high quality research results to its partners in the pharmaceutical and biotechnology industry. In proprietary projects, Evotec specialises in finding new treatments for CNS diseases. Its lead compound, EVT 201, is in clinical phase I for the treatment of insomnia. In addition, the Company has a number of products in late stage pre-clinical development, the most advanced of which, EVT 101 for the treatment of Alzheimer's disease, is expected to enter clinical trials later this year. In contract research, Evotec provides innovative solutions from target to clinic through an unmatched range of capabilities, incl. early stage assay development/screening through to medicinal chemistry/manufacturing. -0- Company: GTC Biotherapeutics Ticker Symbol & Exchange: GTCB NASDAQ Investor Relations Contact: Thomas Newberry Investor Relations Contact Phone: 508-370-5374 Web: www.gtc-bio.com Date of Presentation: November 7, 2005 at 12:20 pm
GTC Biotherapeutics is a leader in the development, production, and commercialization of therapeutic proteins through transgenic animal technology. GTC currently has five products in its internal pipeline and a portfolio of external program production opportunities. GTC's lead program is ATryn(R), its recombinant form of human antithrombin. A Market Authorization Application is under review by the European Medicines Agency for the use of ATryn(R) in patients with a hereditary antithrombin deficiency. In its external programs, GTC's technology is used to develop transgenic production of its partners' proprietary products, including both large-volume protein therapeutics as well as products that are difficult to produce in significant quantities from conventional recombinant production systems. -0- Company: Halozyme Therapeutics Ticker Symbol & Exchange: AMEX:HTI Investor Relations Contact: Don Markley, Vice President Investor Relations Contact Phone: (310) 691-7100 Web: www.halozyme.com Date of Presentation: Tuesday, November 8, 2005; 9:25 AM
Halozyme is a biopharmaceutical company dedicated to developing and commercializing recombinant human enzymes for the infertility, ophthalmology, and oncology communities. The company's portfolio of products under development is based on intellectual property covering the family of human enzymes known as hyaluronidases. Halozyme's recombinant human enzymes may replace current animal slaughterhouse-derived enzymes that carry potential risks of animal pathogen transmission and immunogenicity. The versatility of the first enzyme, rHuPH20, enables Halozyme to develop the product as a medical device, drug enhancement agent, and therapeutic biologic. -0- Company: Hana Biosciences, Inc. Ticker Symbol & Exchange: AMEX: HBX Investor Relations Contact: Russell Skibsted Investor Relations Contact Phone: 650-588-6464 Web: www.hanabiosciences.com Date of Presentation: November 8, 2005, 9:45AM, Holmes II
Hana Biosciences (AMEX: HBX) acquires, develops, and commercializes innovative products to advance cancer care. Product pipeline includes: (1) Talotrexin (PT-523), a novel nonpolyglutamatable antifolate drug which has demonstrated enhanced antitumor activity in a broad spectrum of cancers by targeting DHFR to prevent DNA synthesis and inhibit tumor growth in Ph I/II clinical trials in NSCLC, ALL, and solid tumors;(2) Zensana(TM) (ondansetron oral spray), a novel, proprietary oral spray formulation of ondansetron that uses the highly-absorptive surfaces of the oral mucosa to deliver drug directly into the blood stream to prevent chemotherapy-induced nausea and vomiting being developed under 505(b)(2) registration for 2007 launch; and(3) IPdR, a novel, orally available, thymidine analogue and prodrug for IUdR, in Ph I clinical trials in colorectal, liver, gastric, and pancreatic cancers -0- Company: Insmed Incorporated Ticker Symbol & Exchange: INSM Investor Relations Contact: Baxter Phillips, III Investor Relations Contact Phone: 804.565.3041 Web: www.insmed.com Date of Presentation: November 7, 2005
Insmed is a biopharmaceutical company focused on the discovery and development of drug candidates for the treatment of metabolic diseases and endocrine disorders with unmet medical needs. -0- Company: INYX, INC. Ticker Symbol & Exchange: IYXI: OTCBB Investor Relations Contact: Jay M. Green, Executive VP Investor Relations Contact Phone: 212-838-1111 Web: www.inyxinc.com Date of Presentation: November 7, 2005
Inyx, Inc. is a specialty pharmaceutical company with niche drug delivery technologies and products for the treatment of respiratory, allergy, dermatological, topical and cardiovascular conditions. Inyx focuses its expertise on both prescription and over-the-counter pharmaceutical products, and provides specialty pharmaceutical development and production consulting services. In addition, Inyx is developing its own proprietary products to be marketed by selected clients and strategic partners. The company's operations are conducted through several wholly owned subsidiaries: Inyx USA, Ltd., based in Manati, Puerto Rico; Inyx Pharma Limited, near Manchester, England; Inyx Europe Limited, also near Manchester; Inyx Canada, Inc. in Toronto; and Exaeris, Inc., through which Inyx's strategic marketing collaborations are conducted. Inyx, Inc.'s corporate offices are in New York City. -0- Company: Isotechnika Inc. Ticker Symbol & Exchange: ISA:TSX Investor Relations Contact: Stephanie Gillis-Paulgaard Investor Relations Contact Phone: 780-487-1600 extension 243 Web: www.isotechnika.com Date of Presentation: November 7th
Isotechnika Inc. is an international biopharmaceutical company headquartered in Edmonton, Alberta, Canada. Drawing upon its expertise in medicinal chemistry and immunology, the Company is focused on the discovery and development of novel immunosuppressive therapeutics that are safer than currently available treatments. Isotechnika's lead compound, ISA247 is an immunosuppressant currently in a Canadian Phase III human clinical trial for the treatment of moderate to severe psoriasis. In addition, a Phase IIb kidney transplant trial with ISA247 will commence by the end of 2005. The Company also has two additional immunosuppressive compounds in its drug pipeline, TAFA93 and TKB662 which are in Phase I and pre-clinical respectively. -0- Company: Lipid Sciences, Inc. Ticker Symbol & Exchange: LIPD, Nasdaq Investor Relations Contact: Deborah S. Lorenz Investor Relations Contact Phone: 925-249-4031 Web: www.lipidsciences.com Date of Presentation: November 8, 2005
Lipid Sciences is a development-stage biotechnology company engaged in researching and developing products and processes to treat major medical indications, in which lipids (fat components) play a key role. The HDL Therapy platform (selective HDL delipidation and HDL mimetic peptides) focuses on reversing plaque build-up in the vascular system and coronary arteries thereby reducing acute coronary events. The Viral Immunotherapy platform focuses on removing lipid coatings from lipid-enveloped viruses, through delipidation technology, to stimulate the body's immune system to fight disease. Conditions that could be impacted by this technology include HIV, Hepatitis B and C, West Nile, SARS and influenza. -0- Company: MaxCyte, Inc. Investor Relations Contact: Ronald Holtz, CFO Investor Relations Contact Phone: 301-944-1624 Web: www.maxcyte.com Date of Presentation: November 8, 2005 at 12:40 PM EST
MaxCyte Inc. is a clinical stage company developing cell-based therapeutics primarily in the areas of oncology and regenerative medicine. MaxCyte's pipeline includes one product in Phase I/II clinical trials for the treatment of Chronic Lymphocytic Leukemia (CLL) and several preclinical candidates to treat a variety of diseases with unmet needs. The company also offers its unparalleled, customizable flow based cell loading technology to partners who take advantage of its advanced capabilities for cell-based therapeutic development and biotherapeutic (viral vector) manufacturing through licensing relationships. Partners are currently working to develop therapeutics for pulmonary, cardiovascular and infectious disease, cancer and regenerative medicine. -0- Company: MEDICURE INC Ticker Symbol & Exchange: Amex: MCU & TSX: MPH Investor Relations Contact: HOGAN MULLALLY Investor Relations Contact Phone: 204-487-7412 Web: www.medicure.com Date of Presentation: Nov. 8, 2005
Medicure Inc. is a cardiovascular drug discovery and development Company focused on developing effective therapeutics for unmet needs in the field of cardiovascular medicine, the largest pharmaceutical market sector. The Company's solid position in this field is supported by the following attributes -- Cardiovascular focused pipeline: a global market of over US $70 billion -- Two drugs - MC-1 & MC-4232 - in advanced clinical development -- Three positive Phase II trials completed -- Unique products addressing major markets not adequately served by existing drugs -- Dual action antithrombotic, MC-45308, in preclinical testing Medicure also has a medicinal chemistry based Drug Discovery program focused on discovery and advancement of novel small molecule, anti-ischemics and anti-thrombotics towards human clinical studies. -0- Company: MethylGene Inc. Ticker Symbol & Exchange: TSX : MYG Investor Relations Contact: Andrea Gilpin, Ph.D. Investor Relations Contact Phone: 514-337-3333 ext 416 Web: www.methylgene.com Date of Presentation: November 8, 2005
MethylGene is a biopharmaceutical specializing in cancer, antibiotic resistance, and other diseases such as diabetes, Huntington's, antifungals and inflammation. We currently have two compounds in human clinical trials: MGCD0103 and MG98. We have successfully partnered with Taiho Pharmaceutical, MGI Pharma, Merck and EnVivo Pharmaceuticals. MethylGene's in-house medicinal chemistry group synthesizes compounds that specifically target enzymes involved in certain diseases such as cancer. The ability to synthesize specific compounds allows MethylGene to target diseased cells leaving healthy cells untouched. This is in contrast to other approaches such as chemotherapy or radiation therapy in which both healthy and diseased cells are affected causing unnecessary side effects. Our strength is in our ability to discover, to develop, and deliver target-specific drugs. -0- Company: MicroIslet Inc. Ticker Symbol & Exchange: Amex: MII Investor Relations Contact: Bill Kachioff Investor Relations Contact Phone: 858-657-0287 Web: www.microislet.com Date of Presentation: 11/8/05
MicroIslet is a biotechnology company engaged in the research, development, and commercialization of patented technologies in the field of transplantation therapy for people with insulin-dependent diabetes. MicroIslet's patented islet transplantation technology includes methods for isolating, culturing, cryopreservation, and immuno-protection (microencapsulation) of islet cells. MicroIslet is working to develop and commercialize a first product, called MicroIslet-Px(TM), a microencapsulated porcine islet cell suspension that will be used for transplantation in patients with insulin-dependent diabetes. Additional information about MicroIslet can be found at www.microislet.com. -0- Company: Neoprobe Corporation Ticker Symbol & Exchange: NEOP (OTCBB) Investor Relations Contact: Brent Larson Investor Relations Contact Phone: 614.793.7500 x133 Web: www.neoprobe.com Date of Presentation: November 8, 2005 (1:00p.m.)
Neoprobe is a biomedical company focused on developing and commercializing innovative products that enhance patient care and improve patient outcome. Neoprobe currently markets the neo2000(R) line of gamma detection systems that are widely used by cancer surgeons and is commercializing the Quantix(R) line of blood flow measurement products. Neoprobe holds significant interests in the development of related biomedical systems and radiopharmaceutical agents including Lymphoseek(TM) and RIGScan(R) CR. Neoprobe's subsidiary, CIRA Biosciences, Inc., is also advancing a patient-specific cellular therapy technology platform called ACT. Neoprobe's strategy is to deliver superior growth and shareholder return by maximizing its strong position in gamma detection technologies and diversifying into new, synergistic biomedical markets through continued investment and selective acquisitions. -0- Company: NeuroHealing Pharmaceuticals, Inc. Investor Relations Contact: Daniel Katzman Investor Relations Contact Phone: 617 331-4111 Web: www.neurohealing.com Date of Presentation: November 8, 2005
NeuroHealing is a private, clinical stage company developing therapeutics to improve the functional outcome of post-acute neurorehabilitation patients, including disorders such as traumatic brain injury, stroke, Parkinson's disease and other motor neuron diseases. NeuroHealing is developing three reprofiled drug candidates, each with early evidence of clinical efficacy, extensive human safety data and featuring formulation and drug delivery strategies:NH001 is designed to accelerate the recovery and improve the functional outcome of patients from a coma, vegetative or minimally conscious state following a traumatic brain injury. NH004 is a novel treatment for sialorrhea (drooling), an embarrassing complication in Parkinson's, Cerebral Palsy and other neurological conditions. NH02D is designed to improve the rehabilitation outcomes of stroke patients. -0- Company: NovaDel Pharma Ticker Symbol & Exchange: AMEX NVD Investor Relations Contact: Michael Spicer Investor Relations Contact Phone: Michael Spicer, 908.782.3431 X2550 Web: www.novadel.com Date of Presentation: November 7, 2005
NovaDel Pharma Inc. is a specialty pharmaceutical company that is developing a novel drug-delivery system for both prescription and over-the-counter therapeutics. The Company's proprietary technology uses an oral spray to rapidly deliver drugs into the systemic circulation. The technology can be applied to a variety of drugs in the Rx, OTC and veterinary therapeutic areas. Drugs administered in a spray form to the oral mucosa have the potential for a) faster onset of action, b) improved safety profile and c) enhanced patient compliance. -0- Company: OrthoLogic Corp. Ticker Symbol & Exchange: OLGC Investor Relations Contact: Sherry Sturman Investor Relations Contact Phone: 602-286-5436 Web: www.orthologic.com Date of Presentation: Monday, November 7, 2005 8:00 a.m.
OrthoLogic is a biotechnology company focused on the development and commercialization of the novel synthetic peptide Chrysalin(R) (TP508) in three lead indications, all of which represent areas of significant unmet medical need - fracture repair, diabetic foot ulcer healing and cartilage defect repair. Based on the Company's pioneering scientific research of the natural healing cascade, OrthoLogic has become the leading company focused on tissue and bone repair. OrthoLogic is committed to developing a pipeline of novel peptides and other molecules aimed at helping patients with unmet medical needs and under-served conditions. The Company maintains exclusive worldwide rights for Chrysalin. -0- Company: OXiGENE, Inc. Ticker Symbol & Exchange: Nasdaq/XSSE: OXGN Investor Relations Contact: Susan Hager Investor Relations Contact Phone: 781-547-5900 Web: www.oxigene.com Date of Presentation: Nov. 8, 2005
OXiGENE is an emerging pharmaceutical company developing novel small-molecule therapeutics to treat cancer and eye diseases. The Company's major focus is the clinical advancement of drug candidates that selectively disrupt abnormal blood vessels associated with solid tumor progression and visual impairment. OXiGENE is dedicated to leveraging its intellectual property position and therapeutic development expertise to bring life saving and enhancing medicines to patients. -0- Company: PAION Ticker Symbol & Exchange: PA8 Investor Relations Contact: Dr. Peer Nils Schroder Investor Relations Contact Phone: +49-241-4453-152 Web: www.paion.de Date of Presentation: 7.11.2005, 10.10 a.m.
PAION, a biopharmaceutical company based in Aachen, Germany, aims to become a leader in developing and commercialising innovative drugs for the treatment of stroke and other thrombotic diseases for which there is a substantial unmet medical need. PAION intends to build an integrated drug portfolio by exploiting its expertise in identifying compounds, licensing or otherwise acquiring them and advancing them through the clinical development and regulatory approval process. PAION's lead product Desmoteplase for the treatment of acute ischaemic stroke is currently in Phase III. During the first half-year 2005, PAION employed on average 59 people. -0- Company: Panacos Pharmaceuticals, Inc. Ticker Symbol & Exchange: PANC (Nasdaq) Investor Relations Contact: Jill Smith Investor Relations Contact Phone: 240.631.1395 x-1250 Web: http://www.panacos.com Date of Presentation: November 7, 2005
Panacos is developing the next generation of anti-infective products through discovery and development of small molecule oral drugs for the treatment of HIV and other major human viral diseases. Panacos' proprietary discovery technologies and lead therapeutic candidate, PA-457, focus on novel targets in the virus life cycle, including virus maturation and virus fusion. -0- Company: PharmaFrontiers Corp. Ticker Symbol & Exchange: PFTR.OB Investor Relations Contact: C. W. "Bill" Rouse, CFO Investor Relations Contact Phone: 281-775-0608 Web: www.pharmafrontierscorp.com Date of Presentation: November 9, 2005 (9:45 AM) Kennedy II
PharmaFrontiers' strategy is to develop and commercialize cell therapies to treat several major disease areas such as cardiac and pancreatic conditions and Multiple Sclerosis. PharmaFrontiers owns patented and proprietary individualized cell therapies that are in FDA Phase I/II human dose ranging clinical trials to evaluate their safety and effectiveness in treating MS. The company also holds the exclusive worldwide license from the University of Chicago, through its prime contractor relationship with Argonne National Laboratory, for patents relating to the use of adult pluripotent stem cells derived from patients' own circulating blood. -0- Company: Protein Polymer Technologies, Inc. Ticker Symbol & Exchange: OTC BB: PPTI Investor Relations Contact: Erin Davis Investor Relations Contact Phone: (858) 558-6064 x 120 Web: www.ppti.com Date of Presentation: Wednesday, November 9, 2005
Protein Polymer Technologies, Inc. is a biotechnology company that discovers and develops innovative therapeutic devices to improve medical and surgical outcomes. The Company focuses on developing technology and products to be used for soft tissue augmentation, tissue adhesives and sealants, wound healing support and drug delivery devices. Protein Polymer Technologies' proprietary protein-based biomaterials are uniquely tailored to optimize clinical performance and contain no human or animal components that could potentially transmit or cause disease. The company is headquartered in San Diego, California. For additional information about the company, please visit www.ppti.com. -0- Company: Regeneration Technologies, Inc. Ticker Symbol & Exchange: RTIX, NASDAQ Investor Relations Contact: Wendy Crites Wacker Investor Relations Contact Phone: (386) 418-8888 Web: www.rtix.com Date of Presentation: November 8, 2005
RTI processes allograft and xenograft tissue into shaped implants for use in orthopedic, cardiovascular and other surgeries with a commitment to science, safety and innovation. RTI also holds the patents on BioCleanse(R), the only proven tissue sterilization process validated to eliminate viruses, bacteria, fungi and spores from tissue without impacting the structural or biomechanical integrity of the tissue. The company has distributed more than 600,000 allograft implants sterilized with the BioCleanse process with zero incidence of infection. RTI is accredited by the American Association of Tissue Banks and was named a 2004 Technology Pioneer by the World Economic Forum. -0- Company: Santarus Inc. Ticker Symbol & Exchange: Nasdaq: SNTS Investor Relations Contact: Jody Cain, Senior VP Investor Relations Contact Phone: (310) 691-7100 Web: www.santarus.com Date of Presentation: Wed., November 9, 2005, 9:25 AM
Santarus, Inc. is a specialty pharmaceutical company focused on acquiring, developing and commercializing proprietary products to enhance the quality of life for patients with gastrointestinal diseases and disorders. The company's current products are immediate-release formulations of omeprazole, a widely prescribed proton pump inhibitor (PPI). The company launched its first product, ZEGERID(R) Powder for Oral Suspension 20 mg, in October 2004 and launched ZEGERID Powder for Oral Suspension 40 mg in February 2005. The company submitted a New Drug Application (NDA) for ZEGERID Capsules to the U.S. Food and Drug Administration (FDA) in April 2005 and submitted an NDA for ZEGERID Chewable Tablets to the FDA in May 2005. More information about Santarus is available on the company's Web site at www.santarus.com. -0- Company: Solexa Inc. Ticker Symbol & Exchange: Nasdaq: SLXA Investor Relations Contact: Jody Cain, Senior VP Investor Relations Contact Phone: (310) 691-7100 Web: www.solexa.com Date of Presentation: Tuesday, November 8, 2005; 4:35 PM
Solexa is developing and preparing to commercialize a new genetic analysis instrument system which will be used to perform a range of analyses including whole genome resequencing, gene expression analysis and micro-RNA analysis. Solexa scientists have sequenced a human bacterial artificial chromosome, an important milestone demonstrating that its technology can be applied to resequence human DNA. Solexa expects its first-generation technology to generate over a billion bases of DNA sequence per run and to enable whole genome resequencing below $100,000 per sample, making it the first platform to reach this important milestone. Solexa's longer-term goal is to reduce the cost of human resequencing to a few thousand dollars for use in a wide range of applications from basic research through clinical diagnostics. Solexa expects to introduce its first instrument system by the end of 2005. -0- Company: Spectranetics Corporation Ticker Symbol & Exchange: Nasdaq: SPNC Investor Relations Contact: Don Markley, Vice President Investor Relations Contact Phone: (310) 691-7100 Web: www.cytrx.com Date of Presentation: Wed., November 9, 2005; 11:55 AM
Spectranetics is a medical device company that develops, manufactures and markets single-use medical devices used in minimally invasive surgical procedures within the cardiovascular system in conjunction with its proprietary excimer laser system. Its CVX-300(R) excimer laser is the only system approved by the FDA for multiple cardiovascular procedures, including coronary atherectomy, and the removal of problematic pacemaker and defibrillator leads. Nearly all of the company's FDA-approved and investigational applications have received Communautes Europeennes (CE) mark registration for marketing within Europe. In April 2004 Spectranetics obtained 510(k) clearance from the FDA for the laser-based treatment of patients suffering from total occlusions (blockages) in their leg arteries that are not crossable with a guide wire. -0- Company: StemCells, Inc. Ticker Symbol & Exchange: Nasdaq: STEM Investor Relations Contact: Rodney Young, CFO Investor Relations Contact Phone: 650 475 3100 ext 105 Web: www.stemcellsinc.com Date of Presentation: November 7, 2005
StemCells, Inc. is developing stem cell therapeutics using adult stem cell technology. The Company to date has discovered the human neural stem cell (HuCNS-SC(TM)) and candidate liver and pancreatic stem cells. StemCells has over 40 issued US patents in the neural stem cell field. StemCells' initial target indications are lysosomal storage diseases that affect the CNS, and in October 2005, the FDA cleared the Company to begin a Phase I clinical trial in Batten disease. This will be the first FDA-approved trial to transplant human neural stem cells. StemCells is continuing preclinical evaluation of HuCNS-SC as a treatment for spinal cord injury, stroke and other CNS indications. -0- Company: TRANSGENE Ticker Symbol & Exchange: TRGNY (Pink Sheets) Investor Relations Contact: Philippe Poncet Investor Relations Contact Phone: + 33 3 88 27 91 21 Web: www.transgene.fr Date of Presentation: November 8, 2005
Transgene is a France-based biopharmaceutical company dedicated to the development of therapeutic vaccines and immunotherapeutic products in oncology and infectious diseases. The company has three compounds in Phase II trials and one compound in Phase I study. Transgene has bio-manufacturing capacities for the production of viral-based vectors (adenovirus and vaccinia virus) and technologies available for out-licensing.
By developing expertise in applied research, clinical and production capabilities (2800 sq. meter GMP production facility) while maintaining broad intellectual property of over 200 patent families, Transgene is uniquely poised to advance cancer and infectious diseases therapies through both in-house and partnered development. -0- Company: Transition Therapeutics Ticker Symbol & Exchange: TTH Investor Relations Contact: Soraya Centeno Investor Relations Contact Phone: 416 260 7770 ext. 243 Web: www.transitiontherapeutics.com Date of Presentation: November 8th at 11:55am
Transition Therapeutics is a product-focused biopharmaceutical company, developing novel therapeutics for disease indications with large markets. The company's strategy is to develop multiple products in parallel, thereby leveraging its internal resources and expertise across many opportunities. Transition's development focus is to concentrate on preclinical products that can be quickly advanced to Phase II trials for large disease indications. Transition is currently developing five products that target diabetes (Type I and II), multiple sclerosis, hepatitis C and Alzheimer's disease (Alzheimer's disease-modifying therapy). Transition's robust product pipeline and recent licensing agreement with leading diabetes company Novo Nordisk demonstrate the Company's ability to develop multiple clinical programs in parallel and attract large pharma partnerships. -0- Company: VioQuest Pharmaceuticals Ticker Symbol & Exchange: OTCBB: VQPH Investor Relations Contact: Amanda Watkins Investor Relations Contact Phone: 212-825-3210 Web: www.vioquestpharm.com Date of Presentation: November 9, @ 10:10 AM
VioQuest Pharmaceuticals, Inc. acquires and develops targeted late preclinical and early clinical stage therapies with unique mechanisms of action for oncology, viral and autoimmune disorders. The Company is developing two novel anti-cancer agents VQD-001 and VQD-002 for the treatment of melanoma, myeloma, lymphoma; and breast, ovarian, pancreatic, colorectal cancers, respectively. VioQuest's subsidiary, Chiral Quest, Inc., a pioneer in asymmetric synthesis, offers proprietary chiral catalysts and synthesis expertise for creating important chiral intermediates and products, which improves the safety, efficacy and manufacturing efficiency of pharmaceutical products. Chiral Quest provides products and services to twelve of the top eighteen pharmaceutical companies worldwide. -0- Company: ZIOPHARM Oncology Ticker Symbol & Exchange: ZIOP.OB Investor Relations Contact: Kelly Luethje & Suzanne McKenna Investor Relations Contact Phone: 617-259-1975/ 646-214-0703 Web: www.ziopharm.com Date of Presentation: 8:40-9:00 am
ZIOPHARM Oncology, Inc. is a biopharmaceutical company seeking to acquire, develop and commercialize a diverse, risk-sensitive portfolio of in-licensed cancer drugs that address unmet medical needs. Currently, the Company is in U.S. phase I studies for its two product candidates, ZIO-101 and ZIO-201. -0- Company: ZymoGenetics Ticker Symbol & Exchange: NASDAQ: ZGEN Investor Relations Contact: John Calhoun Investor Relations Contact Phone: 206-442-6744 Web: www.zymogenetics.com Date of Presentation: November 7, 2005
ZymoGenetics is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutic proteins for the prevention or treatment of human diseases. The Company is developing a diverse pipeline of potential proprietary product candidates that are moving into and through clinical development. These span a wide array of clinical opportunities that include bleeding, autoimmune diseases and cancer. ZymoGenetics intends to commercialize these product candidates through internal development, collaborations with partners, and out-licensing of patents from its extensive patent portfolio. For further information, visit www.zymogenetics.com.
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