SHIRE PLC - Statement re: waiver of notice of AbbVie's Board meeting

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION (IN WHOLE OR IN PART) IN, INTO OR
   FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE
                      RELEVANT LAWS OF SUCH JURISDICTION

For immediate release 15 October 2014

                                   Shire plc

           Statement re: waiver of notice of AbbVie's Board meeting

Shire plc announces that, in order to allow the period of uncertainty for its
shareholders, employees and other stakeholders to be reduced, it has agreed to
waive the requirement for three business days' notice for AbbVie's Board to
meet to consider its recommendation of the offer for Shire.

CONTACTS

Shire

Stephanie Fagan                                              [phone]
Jeff Poulton                                                 [phone]
Sarah Elton-Farr                                             [phone]

FTI Consulting (Media Adviser to the Company)
Ben Atwell (London)                                          [phone]

Evercore (Financial Adviser to the Company)
Francois Maisonrouge                                         [phone]
Edward Banks

Morgan Stanley (Financial Adviser to the Company)
Michele Colocci                                              [phone]
Colm Donlon
Peter Moorhouse (Corporate Broking)

Deutsche Bank (Financial Adviser to the Company)
Nick Bowers (Corporate Broking)                              [phone]
Ben Lawrence (Corporate Broking)

Citi (Financial Adviser to the Company)
Christopher Hite                                             [phone]

Goldman Sachs (Financial Adviser to the Company)
Raj Shah                                                     [phone]


A copy of this announcement will be available at www.shire.com. The content of
the website referred to in this announcement is not incorporated into and does
not form part of this announcement.

FURTHER INFORMATION

Evercore Partners International LLP ("Evercore"), which is authorised and
regulated in the United Kingdom by the Financial Conduct Authority, is acting
as financial adviser exclusively for Shire and no one else in connection with
the matters referred to in this announcement and will not regard any other
person as its client in relation to the matters referred to in this
announcement and will not be responsible to anyone other than Shire for
providing the protections afforded to clients of Evercore, nor for providing
advice in relation to the matters referred to in this announcement.

Morgan Stanley & Co. International plc, which is authorised by the Prudential
Regulation Authority and regulated by the Financial Conduct Authority and the
Prudential Regulation Authority in the United Kingdom, is acting as financial
adviser to Shire and no one else in connection with the matters referred to in
this announcement. In connection with such matters, Morgan Stanley & Co.
International plc, its affiliates and its and their respective directors,
officers, employees and agents will not regard any other person as their
client, nor will they be responsible to any other person other than Shire for
providing the protections afforded to their clients or for providing advice in
connection with the contents of this announcement or any other matter referred
to herein.

Citigroup Global Markets Limited, which is authorised by the Prudential
Regulation Authority and regulated by the Financial Conduct Authority and the
Prudential Regulation Authority, each in the United Kingdom, is acting as
financial adviser to Shire and for no one else in connection with the matters
set out in this announcement. In connection with such matters, Citigroup Global
Markets Limited, its affiliates and its and their respective directors,
officers, employees and agents will not regard any other person as their
client, nor will they be responsible to anyone other than Shire for providing
the protections afforded to its clients or for providing advice in connection
with the contents of this announcement or any matter referred to herein.

Goldman Sachs International, which is authorised by the Prudential Regulation
Authority and regulated by the Financial Conduct Authority and the Prudential
Regulation Authority in the United Kingdom, is acting as financial adviser to
Shire and no one else in connection with the matters referred to in this
announcement. In connection with such matters Goldman Sachs International, its
affiliates and its and their respective directors, officers, employees and
agents will not regard any other person as their client, nor will they be
responsible to anyone other than Shire for providing the protections afforded
to clients of Goldman Sachs International, or for giving advice in connection
with the contents of this announcement or any other matter referred to herein.

Deutsche Bank AG is authorised under German Banking Law (competent authority:
BaFIN - Federal Financial Supervisory Authority). Deutsche Bank AG, London
Branch is further authorised by the Prudential Regulation Authority and is
subject to limited regulation by the Financial Conduct Authority and Prudential
Regulation Authority. Deutsche Bank is acting as financial adviser to Shire and
no one else in connection with the contents of this Announcement and will not
be responsible to anyone other than Shire for providing the protections
afforded to its clients or for providing advice in connection with the contents
of this Announcement or any matter referred to herein.