Notification of major interests in shares
October 31, 2014 - Shire plc (LSE: SHP, NASDAQ: SHPG)
1. Identity of the issuer or the underlying issuer of existing shares to Shire plc
which voting rights are attached:
2. Reason for the notification State
Yes/
No
An acquisition or disposal of voting rights Yes
An acquisition or disposal of qualifying financial instruments which may
result in the acquisition of shares already issued to which voting rights
are attached No
An acquisition or disposal of instruments with similar economic effect to
qualifying financial instruments
No
An event changing the breakdown of voting rights No
Other (please specify): No
3. Full name of person(s) subject to the notification obligation: FMR LLC
4. Full name of shareholder(s) (if different from 3.): See Section 9
5. Date of the transaction (and date on which the threshold is 30th October 2014
crossed or reached if different):
6. Date on which issuer notified: 31st October 2014
7. Threshold(s) that is/are crossed or reached: 5%
8. Notified details:
A: Voting rights attached to shares
Situation previous to Resulting situation after the triggering
the Triggering transaction
Class/type transaction
of shares
if possible Number Number Number Number of voting % of voting
using the of of of rights rights
ISIN CODE Shares Voting shares
Rights
Indirect Direct Indirect Direct Indirect
JE00B2QKY057 29,221,937 29,221,937 29,648,433 29,648,433 5.02
B: Qualifying Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of
financial date Conversion rights that may be voting
instrument Period/ Date acquired if the rights
instrument
is exercised/converted
C: Financial Instruments with similar economic effect to Qualifying Financial
Instruments
Resulting situation after the triggering transaction
Type of Exercise Expiration Exercise/ Number of % of voting
financial price date Conversion voting rights
instrument period rights
instrument
refers to
Nominal Delta
Total (A+B+C)
Number of voting rights % of voting rights
29,648,433 5.02
9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:
Custodian Day to Day IM Total
CROSBY ADVS LLC-CROSBY ADVISORS LLC 16,700
BANK OF NEW YORK MELLON FMRC-FMR CO., INC 18,800
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 160,094
BROWN BROTHERS HARRIMAN AND CO FMR UK-FIDELITY MANAGEMENT & RESEARCH (U.K.) INC. 42,900
FMRC-FMR CO., INC 6,548,374
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 16,530
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 264,879
CIBC MELLON TRUST (C) PGA ULC-PYRAMIS GLOBAL ADVISORS (CANADA) ULC 38,200
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 6,523
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 13,200
CITIBANK NA FMRC-FMR CO., INC 3,724,065
CITIBANK NA, HONG KONG BR (S) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 7,197
DEUTSCHE BANK ALEX BROWN (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 3,600
GOLDMAN SACHS AND CO PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 7,200
JP MORGAN, BOURNEMOUTH (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 3,257
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 16,395
JPMORGAN CHASE BANK FMR UK-FIDELITY MANAGEMENT & RESEARCH (U.K.) INC. 422,700
FMRC-FMR CO., INC 7,704,519
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 900
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 13,523
SELECTCOLLC-FIDELITY SELECTCO, LLC 150
MELLON BANK NA (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 48,242
MORGAN STANLEY AND CO LLC PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 1,200
NATIONAL BANK TRUST (C) PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 6,880
NATIONAL FINANCIAL SERVICES(C) SAI-STRATEGIC ADVISERS, INC. 1,603
NORTHERN TRUST CO (C) FMR UK-FIDELITY MANAGEMENT & RESEARCH (U.K.) INC. 1,110,100
FMRC-FMR CO., INC 1,972,600
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 88,401
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 11,550
ROYAL TRUST- TORONTO (C) PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 4,043
STATE STR BK AND TR CO LNDN (C PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 5,172
STATE STREET BANK AND TR CO FMR UK-FIDELITY MANAGEMENT & RESEARCH (U.K.) INC. 532,100
FMRC-FMR CO., INC 5,960,380
PGA ULC-PYRAMIS GLOBAL ADVISORS (CANADA) ULC 504,500
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 228,057
PGATC-PYRAMIS GLOBAL ADVISORS TRUST COMPANY 136,032
US BANK NA (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 7,868
Grand Total 29,648,433
Proxy Voting:
10. Name of the proxy holder: FMR LLC
11. Number of voting rights proxy holder will acquire: 426,496
12. Date on which proxy holder will acquire voting rights: 30th October 2014
13. Additional information: None
14. Contact name: Nina Collomosse
15. Contact telephone number: fil-regreporting@fil.com, 01737 837092
Contact at Shire plc: Tony Guthrie, Deputy Company Secretary, 01256 894746
For further information please contact:
Investor Relations
Jeff Poulton jpoulton@shire.com +1 781 482 0945
Sarah Elton-Farr seltonfarr@shire.com +44 1256 894157
NOTES TO EDITORS
Shire enables people with life-altering conditions to lead better lives.
Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs.
We focus on providing treatments in Neuroscience, Rare Diseases,
Gastrointestinal, and Internal Medicine and we are developing treatments for
symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas, such as Ophthalmology.
www.shire.com
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