Sequana Medical NV: Sequana Medical Announces New Share Capital Amount and New Number of Shares

PRESS RELEASE
REGULATED INFORMATION
29 January 2020, 07:00 CET

Ghent, Belgium, 29 January 2020 - Sequana Medical NV(Euronext Brussels: SEQUA) (the "Company" or "SequanaMedical"), an innovator in the management of fluid overload in liver disease, malignant ascites and heart failure, announces, in accordance with Article 15 of the Belgian Act of 2 May 2007 on the disclosure of major participations in issuers of which shares are admitted to trading on a regulated market and regarding miscellaneous provisions, that in the context of the capital increase that was announced on 22 January 2020 and completed on 27 January 2020 by means of a private placement through an accelerated bookbuilding procedure, its share capital has increased from EUR 1,306,939.52 to EUR 1,635,006.12 and the number of issued and outstanding shares has increased from 12,611,900 to 15,778,566 ordinary shares, through the issuance of a total of 3,166,666 new shares.

In addition to the outstanding shares, the total number of outstanding subscription rights on the time of this announcement amounts to 1,356,278, which entitles their holders (if exercised) to subscribe to 1,855,825 new shares with voting rights in total, namely:

• 302,804 new shares can be issued upon the exercise of one subscription right that was granted in 2016 to Bootstrap Europe S.C.SP. (the 'Bootstrap Subscription Right');
  
• 301,122 new shares can be issued upon the exercise of 104,378 share options that are still outstanding under the "Executive Share Options" plan for staff members and consultants of the Company, entitling the holder thereof to acquire ca. 2.88 shares when exercising one of his or her share options (the 'Executive Share Options'); and
  
• 1,251,899 new shares can be issued upon the exercise of 1,251,899 share options (each share option having the form of a subscription right) that are still outstanding under the "2018 Share Options" plan for directors, employees and other staff members of the Company and its subsidiaries, entitling the holder thereof to acquire one new share when exercising one of his or her share options (the '2018 Share Options').

For more information, please contact:

Sequana Medical
Lies Vanneste, Director IR
Tel: [phone]
Email: [e-mail]

Consilium Strategic Communications
Amber Fennell, Marieke Vermeersch, Sukaina Virji, Melissa Gardiner
Tel: [phone]
Email: [e-mail]

LifeSci Advisors
Chris Maggos
Tel: [phone]
Email: [e-mail]

About Sequana Medical
Sequana Medical is a commercial stage medical device company developing the alfapump platform for the management of fluid overload in liver disease, malignant ascites and heart failure. Fluid overload is a fastgrowing complication of advanced liver disease driven by NASH (non-alcoholic steatohepatitis) related cirrhosis and a common complication in heart failure. The U.S. market for the alfapump resulting from NASH-related cirrhosis is forecast to exceed €3 billion within the next 10-20 years. The heart failure market for the alfapump DSR (Direct Sodium Removal) is estimated to be over €5 billion in the U.S. and EU5 by 2026. Both indications leverage Sequana Medical's alfapump, a unique, fully implanted wireless device that automatically pumps fluid from the abdomen into the bladder, where it is naturally eliminated through urination.

In the U.S., the company's key growth market, the alfapump has been granted breakthrough device designation by the FDA. The North American pivotal study.

Important Regulatory Disclaimers
The alfapump has not yet received regulatory approval in the U.S. and Canada. Any statement in this pressrelease about safety and efficacy of the alfapump does not apply to the U.S. and Canada because the device iscurrently undergoing clinical investigation in these territories.DSR therapy and alfapump DSR are still in development and it should be noted that any statements in this pressrelease regarding safety and efficacy arise from pre-clinical studies and ongoing clinical investigations whichhave yet to be completed. There is no link between DSR therapy, alfapump DSR and ongoing investigations withthe alfapump system in Europe, the U.S. and Canada.