Ilixadencel, Immunicum's cell-based cancer immunotherapy, has been granted orphan drug designation (ODD) by the FDA as a treatment for gastrointestinal stromal tumours (GIST). The treatment is currently in preparations to start a Phase II trial in GIST, which we expect to begin later this year, in combination with tyrosine kinase inhibitors (TKIs). The ODD award adds to the fast-track designation previously awarded to ilixadencel in GIST in December 2020, highlighting the unmet medical need in this indication. GIST are a rare type of gastrointestinal tumour for which TKIs are commonly prescribed. The ODD award represents further external recognition for ilixadencel and Immunicum's underlying platform, in our view.Den vollständigen Artikel lesen ...