Lexaria highlights DehydraTECH's adverse events improvement opportunity
KELOWNA, BC / ACCESS Newswire / August 6, 2025 / Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms, provides the following glucagon-like peptide-1 ("GLP-1") and obesity industry update.
The market for obesity and diabetes control drugs such as GLP-1 is growing at faster rates than nearly anyone originally anticipated, with revenues now expected to exceed $150 billion by 2030. Today these markets are overwhelmingly dominated by Eli Lilly and Company® and Novo Nordisk®, but with compelling growth opportunities abounding, no less than 39 new GLP-1 drugs are in development from 34 different companies.
These tremendous growth opportunities in the GLP-1 sector have all of these companies racing to deliver improved products to the market. As reported earlier, perhaps the largest opportunity for product improvement is in the area of patient safety. The existing medications in the market today notoriously cause unwanted adverse events ("AEs"), more specifically gastrointestinal ("GI") AEs (nausea, vomiting, diarrhea, and constipation).
To that end, Lexaria is working to position its DehydraTECH drug delivery technology as not only an improved drug absorption/performance enhancer, but also as a vital enabler of reducing side effects of various GLP-1 drugs. The following table summarizes the dramatic improvements in GI AEs that Lexaria has realized when testing all three (semaglutide, tirzepatide, and liraglutide) of the major GLP-1 drugs on the market today with its DehydraTECH ("DHT") technology in an oral format:
Lexaria Study | Control | Test Article | % Reductions vs Control GI AEs |
GLP-1-H24-1 GLP-1-H24-2* GLP-1-H24-3 GLP-1-H24-4** GLP-1-H24-4** GLP-1-H25-5 | Rybelsus® (oral) Rybelsus® (oral) Zepbound® (injectable) Rybelsus® (oral) Rybelsus® (oral) Saxenda® (injectable) | DHT-Rybelsus® (oral) DHT-Rybelsus® (oral) DHT-tirzepatide (oral) DHT-semaglutide (oral) DHT-tirzepatide (oral) DHT-liraglutide (oral) | -60% -100% -57% -43% -57% -31% |
* oral dosing was performed after overnight fasting in all instances, except for GLP-1-H24-2 where fed pre-dosing conditions were applied.
** partial/8-week results from 12-week study
Meanwhile, pharmaceutical companies large and small are jockeying for position in what has effectively become a technological arms race. On May 14th Novo Nordisk® announced that it had struck a collaboration and licensing deal with Septerna to develop molecules of use in the obesity and type 2 diabetes sectors, in return for up front and milestone payments of up to $2.2 billion.
On March 12th Roche® announced it had acquired rights to obesity drug petrelintide from Zealand Pharma A/S® for up to $5.3 billion in payments. The Roche transaction allows them to potentially gain more rapid access to the market sector than may have been possible from its own obesity drug, CT-388 which is still undergoing development and assessment.
Regeneron® launched itself into the GLP-1 arms race with its licensing and milestone deal announced June 2nd, worth up to $1.93 billion to acquire rights to China's Hansoh Pharmaceutical Group's HS-20094 which is a dual GLP-1/GIP receptor agonist.
On April 15th, Merck® announced a licensing deal worth up to $493 million for limited rights to Cyprumed's oral peptide drug delivery technology. What is particularly notable is that these rights are non-exclusive, with additional payments required if Merck® was to exercise their option for exclusive rights.
With an extensive wholly-owned patent portfolio protecting DehydraTECH worldwide, Lexaria continues to take steps to unlock the value of its robust drug delivery platform. As the diabetes control and weight-loss industries continue to focus on GLP-1 and even more advanced drug generations for these and other therapeutic indications, Lexaria remains confident that DehydraTECH is valid for utilization with the right commercial partner(s).
About Lexaria Bioscience Corp. & DehydraTECH
DehydraTECH is Lexaria's patented drug delivery formulation and processing platform technology which improves the way a wide variety of drugs enter the bloodstream, always through oral delivery. DehydraTECH has repeatedly evidenced the ability to increase bio-absorption, reduce side-effects, and deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 50 patents granted and additional patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS
This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the Company relating to the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT:
George Jurcic - Head of Investor Relations
ir@lexariabioscience.com
Phone: 250-765-6424, ext 202
SOURCE: Lexaria Bioscience Corp.
View the original press release on ACCESS Newswire:
https://www.accessnewswire.com/newsroom/en/consumer-and-retail-products/glp-1-%22arms-race%22-broadens-to-include-dozens-of-companies-1057060
