DELRAY BEACH, Fla., Aug. 27, 2025 /PRNewswire/ -- The global Endoscopic Submucosal Dissection Market, valued at US$0.46 billion in 2024, stood at US$0.50 billion in 2025 and is projected to advance at a resilient CAGR of 8.4% from 2025 to 2030, culminating in a forecasted valuation of US$0.75 billion by the end of the period. The increasing adoption of endoscopic submucosal dissection (ESD) in Western countries is becoming a significant growth driver for the global ESD market. While Japan and South Korea have historically led in procedural volume due to early adoption and robust screening programs, North America and Europe are now integrating ESD into routine clinical practice. This shift is driven by a growing awareness of the procedure's curative potential, along with improved access to training through international fellowships, live demonstration courses, and hands-on workshops.
Additionally, the publication of clinical guidelines by leading gastroenterological societies in Western countries has legitimized the use of ESD for treating early-stage gastric, esophageal, and colorectal lesions. Advancements in endoscopic technology, coupled with an increasing number of specialized centers of excellence, are further accelerating this adoption. As ESD gains acceptance and support within Western healthcare systems-particularly due to favorable reimbursement frameworks-its procedural volume is expected to rise, significantly boosting market expansion.
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By product, the endoscopic submucosal dissection (ESD) market is categorized based on product types into gastroscopes & endoscopes, knives, injection agents, tissue retractors, grasp/clips, and other products. In 2024, the gastroscopes & endoscopes segment held the largest share of the global ESD market. The integration of AI-based detection and classification algorithms into endoscope platforms enhances the real-time identification of submucosal lesions, which increases the value of gastroscopes in ESD procedures and drives demand for this segment.
By Indication, The ESD market has been categorized into three segments based on indication: stomach cancer, colon cancer, and esophageal cancer. In 2024, stomach cancer accounted for the largest share of the ESD market. This is because the stomach offers a relatively wide and accessible area for ESD procedures, with fewer anatomical constraints than the esophagus or colon. As a result, the success and safety of procedures are higher, which contributes to the growth of the market.
By geography, in 2024, the Asia Pacific region held the largest share of the endoscopic submucosal dissection (ESD) market. This growth can be attributed to the rapid expansion of ambulatory surgical centers (ASCs), which prefer disposable instruments for their efficiency and speed, thus increasing demand. Additionally, numerous international fellowships and training centers in the Asia Pacific, particularly in Japan and South Korea, are producing a significant number of highly skilled ESD practitioners, which further drives the adoption of these procedures.
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The key players in the endoscopic submucosal dissection market include Olympus Corporation (Japan), FUJIFILM Holdings Corporation (Japan), Medtronic (Ireland), Boston Scientific Corporation (US), Sumitomo Bakelite Co., Ltd. (Japan), Creo Medical Group Plc (UK), HOYA Corporation (Japan), ConMed Corporation (US), STERIS (Ireland), MTW Endoskopie Manufaktur (Germany), Ovesco Endoscopy AG (Germany), Zeon Medical Inc. (Japan), Micro-Tech Endoscopy (China), Karl Storz SE & Co. KG (Germany), and Cook Medical (US), among others. These companies have implemented various growth strategies, including product launches, acquisitions, and expansions, to enhance their market presence and reach in the endoscopic submucosal dissection sector.
Olympus Corporation (Japan):
Olympus Corporation is a leading player in the endoscopic submucosal dissection market. The company's broad and comprehensive product portfolio related to endoscopy equipment is one of its key strengths. Olympus offers a variety of electrosurgical knives for endoscopic submucosal dissection procedures, including the DualKnife, FlexKnife, and HookKnife. The company invests a significant portion of its revenue in research and development to launch technologically advanced products. In 2024, Olympus's total R&D expenditure was USD 687.1 million, an increase from USD 616.1 million in 2023.
FUJIFILM Holdings Corporation (Japan)
FUJIFILM Holdings Corporation is a well-established brand in the endoscopic submucosal dissection market, with operations spanning worldwide. It offers a diverse range of endoscopic devices used for examinations related to esophageal, colorectal, and gastric cancer. The main end users of these products include hospitals, medical facilities, and research organizations. The company aims to maintain its brand value by expanding its geographic presence and promoting technological advancements, ensuring it remains a reliable provider of high-quality products.
Medtronic (Ireland)
Medtronic is a medical technology company that manufactures, designs, develops, and markets a broad range of solutions and medical devices for treating cardiac, spinal, neurological, vascular, and chronic conditions. The company also offers endoscopy products through its Respiratory, Gastrointestinal, and Renal business segment, which focuses on creating physician- and patient-centric solutions. Medtronic operates in over 150 countries worldwide.
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